常用名 | 盐酸醋丁洛尔 | CAS号 | 34381-68-5 |
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价格 | 纯度 | 98.0% | |
备货期 | 10天 | 库存 | 现货 |
产品详情(用途,包装等)
用途: Acebutolol Hydrochloride is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.Target: β-Adrenergic ReceptorAcebutolol is a beta blocker for the treatment of hypertension and arrhythmias. Acebutolol following single intravenous administration (10 mg/kg) to rat results in the plasma clearance of 61.9 mL/min/kg, the volume of distribution of 9.6 L/kg, and an elimination half-life of 1.8 hours. Acebutolol following single intravenous administration (50 mg/kg) to rat results in the plasma clearance of 46.5?mL/min/kg, the volume of distribution of 9.5?L/kg, and an elimination half-life of 2.3?hours [1]. Acebutolol (30 mg/kg) decreases cardiac output by 65% and 31% after 1 min and 10 min measurements, respectively, in Sprague-Dawley rats. Acebutolol (30 mg/kg) significantly reduces regional blood flow (RBF) in most organs either after 1 min or 10 min measurements when compare with the baseline values in Sprague-Dawley rats [2]. 物理化学性质: CAS号:34381-68-5 常用中文名:盐酸醋丁洛尔 常用英文名:Acebutolol HCl 分子式:C18H29ClN2O4 分子量:372.887 密度:N/A 沸点:564.1ºC at 760 mmHg 熔点:141-1430C 闪点:N/A 储存条件:库房通风低温干燥 |