| 常用名 | 5-(3-二甲氨基亚丙基)-二苯并[a,d]环庚三烯盐酸盐 | CAS号 | 6202-23-9 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Cyclobenzaprine Hcl is a skeletal muscle relaxant and a central nervous system (CNS) depressant.Target: 5-HT Receptor 2ACyclobenzaprine is a skeletal muscle relaxant and a central nervous system (CNS) depressant. Cyclobenzaprine was thought to be an alpha 2-adrenoceptor agonist that reduced muscle tone by decreasing the activity of descending noradrenergic neurons. Cyclobenzaprine reduced the monosynaptic reflex amplitude dose dependently and this effect was not inhibited by the alpha 2-adrenoceptor antagonists idazoxan and yohimbine. Cyclobenzaprine-induced monosynaptic reflex depression was not attenuated by noradrenergic neuronal lesions produced by 6-hydroxydopamine. Cyclobenzaprine is a 5-HT2 receptor antagonist and that its muscle relaxant effect is due to inhibition of serotonergic, not noradrenergic, descending systems in the spinal cord [1]. The inhibitory effects of cyclobenzaprine on mono- and polysynaptic reflex potentials are due to the inhibition of descending serotonergic systems through 5-HT(2) receptors in the spinal cord [2]. 物理化学性质: CAS号:6202-23-9 常用中文名:5-(3-二甲氨基亚丙基)-二苯并[a,d]环庚三烯盐酸盐 常用英文名:Cyclobenzaprine hydrochloride 分子式:C20H22ClN 分子量:311.848 密度:N/A 沸点:405.9ºC at 760 mmHg 熔点:216-218ºC 闪点:9℃ 储存条件:-20°C Freezer |