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非西他滨

更新时间:2024-07-15 12:36:22 采购访问:11次

常用名 非西他滨 CAS号 69123-90-6
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Fiacitabine(NSC 382097; FIAC; FOAC) is a selective inhibitior of DNA replication of herpes simplex virus(HSV) with IC50 values of 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively. IC50 value: 2.5/12.6 nM (HSV1/2) [2]Target: HSVFIAC suppressed by 90% the replication of various strains of herpes simplex virus types 1 and 2 at concentrations of 0.0025 to 0.0126 microM. Cytotoxicity was minimal, as determined by trypan blue dye exclusion with norman Vero, WI-38, and NC-37 cell proliferation; the 50% inhibitory dose was 4 to 10 microM in a 4-day assay. FIAC was active at much lower concentrations than arabinosylcytosine, iododeoxyuridine, and arabinosyladenine. It was slightly more active against herpes simplex virus type 1 than acycloquanosine and slightly more toxic to normal cells. FIAC was about 8,000 times more active against the replication of wild-type herpes simplex virus type 1 than against a mutant strain lacking the expression of virus-specified thymidine kinase [2].
物理化学性质:
CAS号:69123-90-6
常用中文名:非西他滨
常用英文名:Fiacitabine
分子式:C9H11FIN3O4
分子量:371.104
密度:2.4±0.1 g/cm3
沸点:524.6±60.0 °C at 760 mmHg
熔点:N/A
闪点:271.1±32.9 °C
储存条件:2-8℃

供应商信息

上海念兴实业有限公司 认证供应商

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商品数:403768件
电话:18916513247
地址:2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai
地区: 上海市 上海市 普陀区
联系人:小陈
联系人电话:0086-021-52280163
邮件:sales@echemcloud.com
网址:http://www.echemcloud.com
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参考价格:$462/10mM*1mLinDMSO
其他供应商价格:
2022-03-04 Fiacitabine
价格:¥18414.0

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