| 常用名 | ABT-107 | CAS号 | 855291-54-2 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: ABT-107 is a potent and selective α7 nAChR agonist with Ki of 0.2-0.6 nM for rat or human cortex α7 nAChRs; displays >100-fold selective versus non-α7 nAChRs and other receptors; potently evokes human and rat α7 nAChR current responses in oocytes (EC50=50-90 nM) enhanced by A-867744; reduces spinal tau hyperphosphorylation in tau/amyloid precursor protein transgenic AD mice; improves cognition in monkey. Alzheimer Disease Phase 2 Discontinued 物理化学性质: CAS号:855291-54-2 常用中文名:ABT-107 常用英文名:ABT-107 分子式:C19H20N4O 分子量:320.388 密度:1.3±0.1 g/cm3 沸点:598.0±50.0 °C at 760 mmHg 熔点:N/A 闪点:315.4±30.1 °C |