2-甲基-1,2,3,4,10,14b-六氢苯并[c]吡嗪并[1,2-a]吡啶并[3,2-f]氮杂卓
更新时间：2024-07-15 12:37:06
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| 常用名 | 米氮平 | CAS号 | 85650-52-8 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Mirtazapine is a potent tetracyclic antidepressant.Target: 5-HT ReceptorMirtazapine, the novel antidepressant, has a dual mode of action. It is a noradrenergic and specific serotonergic antidepressant (NaSSA) that acts by antagonizing the adrenergic alpha2-autoreceptors and alpha2-heteroreceptors as well as by blocking 5-HT2 and 5-HT3 receptors [1].Mirtazapine appears to have a substantial ameliorating effect on hot flushes and perspiration bouts. It is postulated that the 5-HT(2A) blocking properties of mirtazapine is accounted in the symptomatic relief of hot flushes [2]. After 4-24 weeks of treatment, mirtazapine induced downregulation of platelet alpha(2A)-adrenoceptors (up to 34%) and Galphai proteins (up to 28%), and the upregulation of GRK 2 (up to 30%). Treatment with mirtazapine reversed this abnormality and induced downregulation of alpha(2A)-adrenoceptor/Galphai complex [3]. 物理化学性质： CAS号：85650-52-8 常用中文名：米氮平 常用英文名：Mirtazapine 分子式：C17H19N3 分子量：265.353 密度：1.2±0.1 g/cm3 沸点：432.4±45.0 °C at 760 mmHg 熔点：114-116ºC 闪点：215.3±28.7 °C 储存条件：Store at RT |
上海念兴实业有限公司
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- 产品名：米尔塔扎平
- 价格： ￥66.9/100mg ￥254.9/1g ￥609.9/1ml ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$207/10mM*1mLinDMSO