枸橼酸托瑞米芬
更新时间：2024-07-15 12:37:28
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| 常用名 | 枸橼酸托瑞米芬 | CAS号 | 89778-27-8 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Toremifene Citrate(NK 622; FC 1157a) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis.IC50 Value: 1±0.3 μMTarget: Estrogen receptorToremifene is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis and other adverse effects resulting from ADT in men with prostate cancer [1]. in vitro: The growth of Ac-1 cells was inhibited by tamoxifen, toremifene and atamestane in vitro with IC50values of 1.8±1.3μM, 1±0.3μM and 60.4±17.2μM, respectively. The combination of toremifene plusatamestane was found to be better than toremifene or atamestane alone in vitro[2].in vivo: The effect of this combination was then studied in vivo using Ac-1 xenografts grown in ovariectomized female SCID mice. The mice were injected with toremifene (1000μg/day), atamestane (1000μg/day), tamoxifen (100μg/day), or the combination of toremifene plus atamestane. In this study, our results indicate that the combination of toremifene plus atamestane was as effective as toremifene or tamoxifen alone but may not provide any additional benefit over toremifene alone or tamoxifen alone[2].Clinical trail: Prostate cancer diagnosis among men with isolated high-grade intraepithelial neoplasia enrolled onto a 3-year prospective phase III clinical trial of oral toremifene[3]. 物理化学性质： CAS号：89778-27-8 常用中文名：枸橼酸托瑞米芬 常用英文名：Toremifene Citrate 分子式：C32H36ClNO8 分子量：598.083 密度：1.045g/cm3 沸点：535.1ºC at 760 mmHg 熔点：158-164ºC 闪点：277.4ºC 储存条件：-20°C Freezer |
上海念兴实业有限公司
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商品数：403768件
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地址：2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai
地区： 上海市 上海市 普陀区
联系人：小陈
联系人电话：0086-021-52280163
邮件：sales@echemcloud.com
网址：http://www.echemcloud.com
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- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：枸橼酸托瑞米芬
- 价格： ￥1226.9/1g ￥380.9/250mg ￥453.9/1ml ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：￥273/100mg