| 常用名 | SMBA1 | CAS号 | 906440-37-7 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: A potent, and selective Bax agonist (Ki=43.3 nM) that induces conformational changes in Bax by blocking S184 phosphorylation; shows no affinity for other Bcl2 family members, including Bcl2, Bcl-XL, Mcl-1, Bcl-w, Bfl-1/A1, Bid or Bak; facilitates Bax insertion into mitochondrial membranes and forming Bax oligomers, leads to cytochrome c release and apoptosis in human lung cancer cells; potently suppresses lung tumour growth via apoptosis by selectively activating Bax in vivo without significant normal tissue toxicity. 物理化学性质: CAS号:906440-37-7 常用中文名:SMBA1 常用英文名:SMBA 1 分子式:C20H13NO3 分子量:315.322 密度:1.4±0.1 g/cm3 沸点:502.0±38.0 °C at 760 mmHg 熔点:N/A 闪点:205.3±15.2 °C |