| 常用名 | FNDR-20123 free base | CAS号 | 1267502-34-0 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: FNDR-20123 free base is an orally active, safe and a first-in-class anti-malarial HDAC inhibitor with IC50s of 31 nM and 3 nM for Plasmodium and human HDAC, respectively. FNDR-20123 free base exerts anti-malarial activity against Plasmodium falciparum asexual stage (IC50=41 nM) and sexual blood stage (IC50=190 nM for male gametocytes). FNDR-20123 free base inhibits HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8 (IC50=25, 29, 2, 11, and 282 nM, respectively) and inhibits Class III HDAC isoforms at nanomolar concentrations. 物理化学性质: CAS号:1267502-34-0 常用中文名:FNDR-20123 free base 常用英文名:FNDR-20123 free base 分子式:C21H23N5O2 分子量:377.44 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |