Abacavir
更新时间：2025-08-24 20:42:18
采购访问：30次
| 常用名 | 阿巴卡韦 | CAS号 | 136470-78-5 |
|---|---|---|---|
| 价格 | 纯度 | 99.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Abacavir is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. IC50 value:Target: NRTI; reverse transcriptase inhibitorAbacavir is a nucleoside reverse transcriptase inhibitor marketed since 1999 for the treatment of infection with the human immunodeficiency virus type 1 (HIV). Despite its clinical efficacy, abacavir administration has been associated with serious and sometimes fatal toxic events. Abacavir has been reported to undergo bioactivation in vitro, yielding reactive species that bind covalently to human serum albumin, but the haptenation mechanism and its significance to the toxic events induced by this anti-HIV drug have yet to be elucidated. The mechanism underlying abacavir hypersensitivity syndrome is related to the change in the HLA-B*5701 protein product. Abacavir binds with high specificity to the HLA-B*5701 protein, changing the shape and chemistry of the antigen-binding cleft. This results in a change in immunological tolerance and the subsequent activation of abacavir-specific cytotoxic T cells, which produce a systemic reaction known as abacavir hypersensitivity syndrome. 物理化学性质： CAS号：136470-78-5 常用中文名：阿巴卡韦 常用英文名：Abacavir 分子式：C14H18N6O 分子量：286.332 密度：1.7±0.1 g/cm3 沸点：636.0±65.0 °C at 760 mmHg 熔点：161 °C(dec.) 闪点：338.4±34.3 °C 储存条件：0-6°C |
上海化源世纪贸易有限公司
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- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：Abacavir
- 价格：
- 纯度：99.0%
- 备货期：10天
- 联系人：徐经理
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：阿巴卡韦
- 价格： ￥319.9/1ml ￥29.9/250mg ￥779.0/1g ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：￥361/10mg