| 常用名 | CI-898 HCl | CAS号 | 1658520-97-8 |
|---|---|---|---|
| 价格 | 纯度 | 95.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: CI-898 HCl is a lipophilic antifolate inhibitor of dihydrofolate reductase (DHFR). It has enhanced binding to DHFR in the presence of the cofactor NADPH. Cl-898 HCl inhibits cell growth and halts the cell cycle at the G1/S phase in L1210 mouse lymphocytic leukemia cells and is active against methotrexate-resistant cancer cell lines. It also enhances the activity of doxorubicin, cyclophosphamide, and 6-thioguanine (6-TG) in mice with advanced stage P338 leukemia. 物理化学性质: CAS号:1658520-97-8 常用中文名:CI-898 HCl 常用英文名:CI-898 HCl 分子式:C19H26Cl3N5O3 分子量:478.800 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |