| 常用名 | AF12198,人类I型白介素受体拮抗剂 | CAS号 | 185413-30-3 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 µM) or the murine type I receptor (IC50>200 µM). AF12198 inhibits IL-1-induced IL-8 production (IC50=25 nM) and IL-1-induced intercellular adhesion molecule-1 (ICAM-1) expression (IC50=9 nM) in vitro. AF12198 has anti-inflammatory activities and blocks responses to IL-1 in vivo[1]. 物理化学性质: CAS号:185413-30-3 常用中文名:AF12198,人类I型白介素受体拮抗剂 常用英文名:AF12198 分子式:C96H123N19O22 分子量:1895.12000 密度:1.354 g/cm3 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:-20°C, 干燥 |