| 常用名 | Sortin1 | CAS号 | 503837-98-7 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Sortin1 is a chemical genetic-hit molecule that causes specific mislocalization of plant and yeast-soluble and membrane vacuolar markers.IC50 value:Target: Vacuolar markersin vitro: In Arabidopsis seedlings, application of Sortin1 and -2 led to reversible defects in vacuole biogenesis and root development. Sortin1 was found to redirect the vacuolar destination of plant carboxypeptidase Y and other proteins in Arabidopsis suspension cells and cause these proteins to be secreted. Sortin1 treatment of whole Arabidopsis seedlings also resulted in carboxypeptidase Y secretion, indicating that the drug has a similar mode of action in cells and intact plants [1]. Structure-activity relationship studies conducted in Arabidopsis revealed the structural requirements for Sortin1 bioactivity and demonstrated that overlapping Sortin1 substructures can be used to discriminate between vacuolar-flavonoid accumulations and vacuolar-biogenesis defects [2]. 物理化学性质: CAS号:503837-98-7 常用中文名:Sortin1 常用英文名:Sortin1 分子式:C26H19NO6 分子量:441.432 密度:1.5±0.1 g/cm3 沸点:675.4±55.0 °C at 760 mmHg 熔点:N/A 闪点:362.3±31.5 °C 储存条件:2-8℃ |