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呋塞米

更新时间:2025-08-27 08:28:18 采购访问:34次

常用名 呋噻米 CAS号 54-31-9
价格 纯度 99.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Furosemide (Lasix) is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema.Target: NKCC Furosemide (INN/BAN) or frusemide is a loop diuretic used in the treatment of congestive heart failure and edema. It is most commonly marketed by Sanofi under the brand name Lasix, and also under the brand names Fusid and Frumex. It has also been used to prevent Thoroughbred and Standardbred race horses from bleeding through the nose during races.Along with some other diuretics, furosemide is also included on the World Anti-Doping Agency's banned drug list due to its alleged use as a masking agent for other drugs.Furosemide, like other loop diuretics, acts by inhibiting NKCC2, the luminal Na-K-2Cl symporter in the thick ascending limb of the loop of Henle. The action on the distal tubules is independent of any inhibitory effect on carbonic anhydrase or aldosterone; it also abolishes the corticomedullary osmotic gradient and blocks negative, as well as positive, free water clearance.Because of the large NaCl absorptive capacity of the loop of Henle, diuresis is not limited by development of acidosis, as it is with the carbonic anhydrase inhibitors. Additionally, furosemide is a noncompetitive subtype-specific blocker of GABA-A receptors. Furosemide has been reported to reversibly antagonize GABA-evoked currents of α6β2γ2 receptors at uM concentrations, but not α1β2γ2 receptors. During development, the α6β2γ2 receptor increases in expression in cerebellar granule neurons, corresponding to increased sensitivity to furosemide
物理化学性质:
CAS号:54-31-9
常用中文名:呋噻米
常用英文名:Furosemide
分子式:C12H11ClN2O5S
分子量:330.744
密度:1.6±0.1 g/cm3
沸点:582.1±60.0 °C at 760 mmHg
熔点:220 °C (dec.)(lit.)
闪点:305.9±32.9 °C
储存条件:库房低温,通风,干燥

供应商信息

上海化源世纪贸易有限公司 认证供应商

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参考价格:$66/10mM*1mLinDMSO
其他供应商价格:
2022-02-19 Furosemide
价格:¥41.9
2019-03-05 呋塞米
价格:¥425.0
2018-03-03 呋塞米
价格:¥需询单
2018-08-06 呋塞米
价格:¥需询单
2024-05-07 呋塞米,速尿
价格:¥需询单
2022-01-14 呋塞米
价格:¥550.0
2022-01-12 呋塞米
价格:¥680.0
2017-11-25 呋塞米
价格:¥需询单
2022-12-01 呋塞米 Furosemide
价格:¥需询单

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