| 常用名 | EN450 | CAS号 | 793719-01-4 |
|---|---|---|---|
| 价格 | 纯度 | 99.72% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: EN450 is a cysteine-reactive covalent molecular glue degrader targeting NF-κB. EN450 interacts with allosteric C111 in the E2 ubiquitin ligase UBE2D. EN450 induces the ternary complex formation between UBE2D and NFKB1. EN450 exerts its anti-proliferative effects through a Cullin E3 ligase and proteasome-dependent mechanism[1]. 物理化学性质: CAS号:793719-01-4 常用中文名:EN450 常用英文名:EN450 分子式:C11H13ClN2O3S 分子量:288.75 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |