| 常用名 | HSP90抑制剂 | CAS号 | 959763-06-5 |
|---|---|---|---|
| 价格 | 纯度 | 99.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: CH5138303 is a potent and orally active Hsp90 inhibitor. CH5138303 shows high binding affinity for N-terminal Hsp90α, with Kd of 0.52 nM. CH5138303 shows potent anti-proliferative activity against human cancer cell lines (HCT116 and NCI-N87), with IC50 values of 0.098 and 0.066 μM, respectively. CH5138303 shows high oral bioavailability in mice (F=44.0%). CH5138303 shows potent antitumor efficacy in a human NCI-N87 gastric cancer xenograft model[1][2]. 物理化学性质: CAS号:959763-06-5 常用中文名:HSP90抑制剂 常用英文名:CH5138303 分子式:C19H18ClN5O2S 分子量:415.89700 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:-20℃ |