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JNJ-18038683 free base

更新时间:2024-07-17 16:21:00 采购访问:9次

常用名 JNJ-18038683 free base CAS号 851373-91-6
价格 ¥需询单/25mg ¥需询单/100mg ¥需询单/250mg 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
JNJ-18038683 is a potent, selective 5-HT7 receptor antagonist with pKi of 8.19 and 8.20 for rat and human 5-HT7 in cell-based assays; decreases 5-HT (100 nM)-stimulated adenylyl cyclase in rat and human 5-HT7/HEK293 cells with pKb of 8.01 and 7.99, respectively; shows 10-fold selectivity over h5-HT6 receptor, 15-fold selectivity over rat adrenergic α1 receptor, 14- to 25-fold selectivity over the h5-HT2 receptor subtypes, and 20-fold selectivity over h5-HT1B receptor; prolongs rapid eye movement (REM) sleep and decreases REM duration induced by citalopram in vivo.
物理化学性质:
CAS号:851373-91-6
常用中文名:JNJ-18038683 free base
常用英文名:JNJ-18038683 free base
分子式:C20H20ClN3
分子量:337.846
密度:1.3±0.1 g/cm3
沸点:547.6±50.0 °C at 760 mmHg
熔点:N/A
闪点:285.0±30.1 °C

供应商信息

上海念兴实业有限公司 认证供应商

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联系人电话:0086-021-52280163
邮件:sales@echemcloud.com
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2022-11-29 JNJ-18038683 free base
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