2-巯乙基磺酸钠
更新时间：2025-08-21 23:02:26
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| 常用名 | 美司那 | CAS号 | 19767-45-4 |
|---|---|---|---|
| 价格 | ￥15200.0/1kg | 纯度 | 96.0% |
| 备货期 | 3天 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： 2-mercaptoethane sulfonate (Mesna), is a synthetic small molecule, widely used as a systemic protective agent against chemotherapy toxicity, but is primarily used to reduce hemorrhagic cystitis induced by cyclophosphamide.IC50 Value: 182 mM (decreased superoxide anion production stimulated with PMA (tetradecanoylphorbol acetate) in PMN in-vitro); 70mM (inhibited H2O2 production) [3]Target: in vitro: MESNA had no effect on the qualitative and quantitative characteristics of the indicated processes in both the types of the doxorubicin sensitive cells. The combined use of doxorubicin and phosphamide or cyclophosphane the use of MESNA for lowering the urotoxic action of oxazophosphorines had no effect on the biological efficacy of doxorubicin [4].in vivo: AMH-positive follicles were significantly decreased after cisplatin administration, which was significantly reversed when mesna was co-administered with cisplatin. The end product of lipid peroxidation, malondialdehyde (MDA), was significantly increased, but the anti-oxidative enzymatic activity of superoxide dismutase (SOD) and glutathione (GSH) were significantly decreased in cisplatin groups when compared with NS group. In contrast, after co-administration of cisplatin with mesna, MDA was significantly decreased whereas the activity of SOD and the concentration of GSH were increased. Moreover, mesna did not decrease the anti-tumor property of cisplatin in HePG2 cell lines [2]. After head trauma, tissue malondialdehyde levels increased; these levels were significantly decreased by MESNA administration. Caspase-3 levels were increased after trauma, but no effect of MESNA was determined in caspase-3 activity [1].Clinical trial: Effects of Mesna on Homocysteine in Kidney Failure . Phase2 物理化学性质： CAS号：19767-45-4 常用中文名：美司那 常用英文名：MESNA 分子式：C2H5NaO3S2 分子量：164.179 密度：N/A 沸点：N/A 熔点：>240°C dec. 闪点：N/A 储存条件：-20?C Freezer, Under Inert Atmosphere |
中山市迪欣化工有限公司
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- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：2-巯基乙烷磺酸钠
- 价格： ￥1047.9/1ml ￥296.9/25g ￥899.9/100g ￥249.9/25g
- 纯度：95.0%
- 备货期：1天
- 联系人：阿拉丁
- 中山市迪欣化工有限公司
- 广东省 中山市 三角镇
- 产品名：2-巯乙基磺酸钠
- 价格： ￥15200.0/1kg
- 纯度：96.0%
- 备货期：3天
- 联系人：董生
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参考价格：￥398/25g