盐酸胺碘酮
更新时间：2025-12-24 19:59:21
采购访问：33次
| 常用名 | 盐酸胺碘酮 | CAS号 | 19774-82-4 |
|---|---|---|---|
| 价格 | ￥需询单/500g ￥需询单/1kg ￥需询单/25kg ￥需询单/200kg | 纯度 | 0.0% |
| 备货期 | 需询单 | 库存 | 有现货 |
| 产品详情（用途，包装等）
用途： Amiodarone is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM. IC50 Value: 1.5 uM ( inhibit TBARS, LOOH and FPL formation)[1]in vitro: It was found that 10 uM amiodarone induces accumulation of ethidium bromide (5 ug/ml) in Saccharomyces cerevisiae cells. At the same time, in yeast cells with inactivated MDR genes, accumulation of ethidium bromide was 6-fold higher even without amiodarone. Addition of non-lethal concentrations of amiodarone to MDR-deficient cells caused an increase of intracellular ethidium bromide to the level, which was even lower than the level in amiodarone-treated wild-type cells [2]. Cells treated with amiodarone were seen to have detached from the dish, with cell rounding, cytoplasmic blebbing and irregularity in shape. An increase in the sub-G1 phase fraction, from 15.43 to 21.34% and 79.83% and a reduction in the G1 phase fraction, from 48.83 to 41.63% and 11.52%, were observed in cells treated with amiodarone at concentrations of 0.1 and 1 mM, respectively [3].in vivo: Chronic treatment with oral amiodarone for 4 weeks reduced i.p. when myocytes were dialyzed with patch-pipettes containing either 10 mM Na+ or 80 mM Na+. In myocytes from untreated rabbits, acute exposure to amiodarone in vitro reduced i.p. when patch pipettes contained 10 mM Na+ but had no effect on i.p. at 80 mM Na+. Amiodarone had no effect on the voltage dependence of the pump or the affinity of the pump for extracellular K+ either after chronic treatment or during acute exposure [4].Clinical trial: Continuous Versus Episodic Amiodarone Treatment for the Prevention of Permanent Atrial Fibrillation . Phase not specified 物理化学性质： CAS号：19774-82-4 常用中文名：盐酸胺碘酮 常用英文名：Amiodarone HCl 分子式：C25H30ClI2NO3 分子量：681.773 密度：1.58 g/cm3 沸点：635.1ºC at 760 mmHg 熔点：154-158°C 闪点：337.9ºC 储存条件：2-8°C |
盼得（上海）国际贸易有限公司
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- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：盐酸胺碘酮
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：胺碘酮盐酸盐
- 价格： ￥788.0/5g ￥248.0/1g
- 纯度：98.0%
- 备货期：2天
- 联系人：刘佳
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Amiodarone HCl
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：胺碘酮盐酸盐
- 价格： ￥124.9/1g ￥1192.9/25g ￥480.9/5g ￥1059.9/1ml
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 盼得（上海）国际贸易有限公司
- 上海市 上海市 徐汇区
- 产品名：盐酸胺碘酮
- 价格： ￥需询单/500g ￥需询单/1kg ￥需询单/25kg ￥需询单/200kg
- 纯度：0.0%
- 备货期：需询单
- 联系人：叶经理
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参考价格：$66/10mM*1mLinDMSO