| 常用名 | 环吡酮胺 | CAS号 | 29342-05-0 |
|---|---|---|---|
| 价格 | ¥需询单/500g ¥需询单/1kg ¥需询单/25kg ¥需询单/200kg | 纯度 | 0.0% |
| 备货期 | 需询单 | 库存 | 有现货 |
| 产品详情(用途,包装等)
用途: Ciclopirox (Penlac) is a synthetic antifungal agent.Target: AntifungalCiclopirox is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. It is most useful against Tinea versicolor. The mechanism of action of ciclopirox is poorly understood [1]. However, loss of function of certain catalase and peroxidase enzymes has been implicated as the mechanism of action, as well as various other components of cellular metabolism. In a study conducted to further elucidate ciclopirox's mechanism, several Saccharomyces cerevisiae mutants were screened and tested. Results from interpretation of the effects of both the drug treatment and mutation suggested that ciclopirox may exert its effect by disrupting DNA repair, cell division signals and structures (mitotic spindles) as well as some elements of intracellular transport [2]. It acts by inhibiting the membrane transfer system by interrupting the Na+ K+ ATPase [1]. It is currently being investigated as an alternative treatment to ketoconazole for seborrhoeic dermatitis as it suppresses growth of the yeast Malassezia furfur. Initial results show similar efficacy to ketoconazole with a relative increase in subjective symptom relief due to its inherent anti-inflammatory properties [3]. 物理化学性质: CAS号:29342-05-0 常用中文名:环吡酮胺 常用英文名:Ciclopirox 分子式:C12H17NO2 分子量:207.269 密度:1.2±0.1 g/cm3 沸点:350.0±25.0 °C at 760 mmHg 熔点:1440C 闪点:165.5±23.2 °C 储存条件:-20°C Freezer |