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Alpha-羟基阿普唑仑

Alpha-羟基阿普唑仑名称

[ CAS 号 ]:
37115-43-8

[ 中文名 ]:
Alpha-羟基阿普唑仑

[ 英文名 ]:
Alpha-Hydroxyalprazolam

[中文别名 ]:

[英文别名 ]:

MFCD00171226
Alpha-Hydroxyalprazolam

Alpha-羟基阿普唑仑物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
556.1±60.0 °C at 760 mmHg

[ 熔点 ]:
129-134ºC

[ 分子式 ]:
C₁₇H₁₃ClN₄O

[ 分子量 ]:
324.764

[ 闪点 ]:
290.1±32.9 °C

[ 精确质量 ]:
324.077789

[ PSA ]:
60.55000

[ LogP ]:
1.70

[ 外观性状 ]:
白色至灰白色粉末

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.730

[ 储存条件 ]:
-20°C Freezer

[ 水溶解性 ]:
methylene chloride: ~20 mg/mL, clear, colorless to faintly yellow

Alpha-羟基阿普唑仑安全信息

[ 符号 ]:

GHS02, GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H301 + H311 + H331-H370

[ 警示性声明 ]:
P210-P260-P280-P301 + P310-P311

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
36

[ 危险品运输编码 ]:
UN1230 - class 3 - PG 2 - Methanol, solution

[ WGK德国 ]:
3

[ 海关编码 ]:
2933990090

Alpha-羟基阿普唑仑合成路线

详细合成路线

Alpha-羟基阿普唑仑上下游产品

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Alpha-羟基阿普唑仑海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Alpha-羟基阿普唑仑文献

LC-MS/MS analysis of 13 benzodiazepines and metabolites in urine, serum, plasma, and meconium.

Methods Mol. Biol. 603 , 89-105, (2010)

We describe a single method for the detection and quantitation of 13 commonly prescribed benzodiazepines and metabolites: alpha-hydroxyalprazolam, alpha-hydroxyethylflurazepam, alpha-hydroxytriazolam,...

Quantitation of benzodiazepines in blood and urine using gas chromatography-mass spectrometry (GC-MS).

Methods Mol. Biol. 603 , 75-87, (2010)

The benzodiazepine assay utilizes gas chromatography-mass spectrometry (GC-MS) for the analysis of diazepam, nordiazepam, oxazepam, temazepam, lorazepam, alpha-hydroxyalprazolam, and alpha-hydroxytria...

[Pharmacological studies on alprazolam, and its main metabolites, alpha-OH-alprazolam and HB compound (author's transl)].

Igaku Kenkyu. 50(7) , 495-507, (1980)

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