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5'-O-(4,4'-二甲氧基三苯甲基)胸苷

5'-O-(4,4'-二甲氧基三苯甲基)胸苷用途

5'-O-DMT-dT(5'-O-(4,4'-二甲氧基三苯基)胸苷)是一种核苷衍生物,可用于制备寡核苷酸[1]。

5'-O-(4,4'-二甲氧基三苯甲基)胸苷名称

[ CAS 号 ]:
40615-39-2

[ 中文名 ]:
保护胸苷

[ 英文名 ]:
5'-O-Dimethoxytrityl-deoxythymidine

[中文别名 ]:

[英文别名 ]:

5'-O-dimethyltritylthymidine
5'-O-(Bis(4-methoxyphenyl)phenylmethyl)thymidine
EINECS 255-003-1
MFCD00010113
5′-O-(4,4′-Dimethoxytrityl)thymidine
5'-O-Dimethoxytrityl-deoxythymidine
DMTr-dThd
5‘-O-Dimethoxytrityl-deoxythymidine
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]thymidine

5'-O-(4,4'-二甲氧基三苯甲基)胸苷生物活性

[ 描述 ]:

5'-O-DMT-dT(5'-O-(4,4'-二甲氧基三苯基)胸苷)是一种核苷衍生物,可用于制备寡核苷酸[1]。

[ 相关类别 ]:

信号通路 >> 细胞周期/DNA损伤 >> DNA/RNA合成

研究领域 >> 其他

[参考文献]

[1]. Lars Holmberg. Method and means for oligonucleotide synthesis. WO1992009615A1.

5'-O-(4,4'-二甲氧基三苯甲基)胸苷物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 熔点 ]:
114-116 °C (subl.)(lit.)

[ 分子式 ]:
C₃₁H₃₂N₂O₇

[ 分子量 ]:
528.596

[ 精确质量 ]:
528.226013

[ PSA ]:
112.01000

[ LogP ]:
6.97

[ 外观性状 ]:
白色粉末

[ 折射率 ]:
1.596

[ 储存条件 ]:
−20°C

[ 稳定性 ]:
Store in Freezer

5'-O-(4,4'-二甲氧基三苯甲基)胸苷MSDS

5'-O-(4,4'-二甲氧基三苯甲基)胸苷安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
29349990

5'-O-(4,4'-二甲氧基三苯甲基)胸苷合成路线

5'-O-(4,4'-二甲氧基三苯甲基)胸苷上下游产品

5'-O-(4,4'-二甲氧基三苯甲基)胸苷上游产品

5'-O-(4,4'-二甲氧基三苯甲基)胸苷下游产品

5'-O-(4,4'-二甲氧基三苯甲基)胸苷海关

[ 海关编码 ]: 29349990

5'-O-(4,4'-二甲氧基三苯甲基)胸苷文献

Solid-phase synthesis of polynucleotides. II. Synthesis of polythymidylic acids by the block coupling phosphotriester method.

Nucleic Acids Res. 8(22) , 5473-89, (1980)

Synthesis of two oligothymidylic acids, tridecamer and nonadecamer, is described by a rapid and simple solid-phase method on two kinds of polyacrylamide supports derivatized from commercially availabl...

Synthesis of mixed oligodeoxyribonucleotides following the solid phase method.

Nucleic Acids Res. 10(10) , 3291-301, (1982)

A method for the synthesis of mixed dimers, trimers and oligonucleotides on a solid support using monomeric protected nucleoside phosphochloridites (1a-d) has been developed and the different nucleosi...

Synthesis of 14 C-radiolabeled oligonucleotides with a novel phosphoramidite reagent.

Bioorg. Med. Chem. Lett. 8(9) , 1123-6, (1998)

A novel solid-phase synthesis of 5'-radiolabeled oligonucleotides is described. The labeling reaction is carried out by the phosphoramidite method with the aid of [4,6-di-14C]-5'-dimethoxytritylthymid...

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