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双肼屈嗪

双肼屈嗪名称

[ CAS 号 ]:
484-23-1

[ 中文名 ]:
双肼酞嗪

[ 英文名 ]:
dihydralazine

[中文别名 ]:

[英文别名 ]:

1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone
Dihydralazin
Nepresol
1,4-dihydrazinophthanazine
1,4-Dihydrazinophthalazine
Nepresolin
Dihydrallazine
Dihydrallazin
4-Hydrazino-1-hydrazono-1,2-dihydrophthalazine
phthalazine, 1,4-bis(hydrazino)-

双肼屈嗪物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
419.9±28.0 °C at 760 mmHg

[ 熔点 ]:
180ºC

[ 分子式 ]:
C₈H₁₀N₆

[ 分子量 ]:
190.205

[ 闪点 ]:
207.7±24.0 °C

[ 精确质量 ]:
190.096695

[ PSA ]:
108.34000

[ LogP ]:
0.73

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.810

双肼屈嗪毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TH8849900

CHEMICAL NAME :: Phthalazine, 1,4-dihydrazino-

CAS REGISTRY NUMBER :: 484-23-1

BEILSTEIN REFERENCE NO. :: 0183442

LAST UPDATED :: 199703

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C8-H10-N6

MOLECULAR WEIGHT :: 190.24

WISWESSER LINE NOTATION :: T66 CNNJ BMZ EMZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 106 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Vascular - BP lowering not characterized in autonomic section

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

DOSE :: 250 ug/kg

SEX/DURATION :: female 32 week(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Bacteria - Escherichia coli

DOSE/DURATION :: 125 ug/tube

REFERENCE :: ABPLAF Acta Biochimica Polonica. (Polish Biochemical Society, Posteura 3, 01-093 Warsaw, Poland) V.1- 1954- Volume(issue)/page/year: 42,291,1995

双肼屈嗪安全信息

[ 海关编码 ]:
2933990090

双肼屈嗪合成路线

详细合成路线

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双肼屈嗪海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%