147200-03-1

• 常用中文名：N-[(4S,6S)-6-甲基-7,7-二氧代-2-磺酰胺基-5,6-二氢-4H-噻吩并[2,3-b]噻喃-4-基]乙酰胺
• 常用英文名：N-6-Methyl-7,7-dioxo-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl]acetamide
• CAS号：147200-03-1
• 分子式：C₁₀H₁₄N₂O₅S₃
• 分子量：338.42400
• 发布时间：2018-12-06 16:31:31
• 更新时间：2026-07-07 12:58:45

名称

• 中文名: N-[(4S,6S)-6-甲基-7,7-二氧代-2-磺酰胺基-5,6-二氢-4H-噻吩并[2,3-b]噻喃-4-基]乙酰胺
• 英文名: N-((4S,6S)-6-Methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)acetamide
• 中文别名: 多佐胺杂质5; N-(((4S,6S)-6-甲基-7,7-二氧化-2-氨基磺酰基-5,6-二氢-4H-硫代[2,3-B]硫代吡喃-4-基)乙酰胺; N-[4S,6S)-6-甲基-7,7-二氧代-2-磺酰胺基-5,6-二氢-4H-噻吩并[2,3-B]硫代吡喃-4-基]乙酰胺; N-[(4S,6S)-6-甲基-7,7-二氧代-2-磺酰胺基-5,6-二氢-4H-噻吩并[2,3-B]噻喃-4-基]乙酰胺(盐酸多佐胺); N-[(4S,6S)-6-甲基-7,7-二氧代-2-磺酰胺基-5,6-二氢-4H-噻吩并[2,3-B]噻喃-4-基]乙酰胺 (盐酸多佐胺第9步); N-[(4S,6S)-6-甲基-7,7-二氧代-2-磺酰胺基-5,6-二氢-4H-噻吩并[2,3-B; 多佐胺N-乙酰基类似物; N-[(4S,6S)-6-甲基; 盐酸多佐胺中间体9; 多佐胺中间体(D-9); N-[(4S,6S)-6-甲基-7,7-二氧代-2-磺酰胺基-5,6-二氢-4H-噻吩并[2,3-B]噻喃-4-基]乙酰胺; 盐酸多佐胺第9步; 盐酸多佐胺杂质5; 盐酸多佐胺九步中间体
• 英文别名: Dorzolomide hydrochloride intermediate-9; Dorzolamide N-Desethyl N-Acetyl Impurity; N-((4S,6S)-6-Methyl-7,7-dioxido-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)acetami; N-[4S,6S)-6-Methyl-7,7-dioxo-2-sulfomyl-5,6-dihydro-4H-thieno[2,3-b] thiopyran-4-yl] acetamide; N-((4S,6S)-6-Methyl-7,7-dioxido-2-sulfaMoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)acetaMide; N-((4S,6S)-6-Methyl-7,7-dioxo-2-sulfamoyl-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-4-yl)-acetamide; N-[(4S,6S)-6-methyl-7,7-dioxo-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl]acetamide; N-(4S,6S)-4-ACETAMIDE-5,6-DIHYDRO-6-METHYL-2-SULFO; N-[(4S,6S)-6-Methyl-7,7-dioxo-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-β]thiopyran-4-yl]acetamide; Dorzolomide hydrochloride int9; Acetamide, N-[(4S,6S)-2-(aminosulfonyl)-5,6-dihydro-6-methyl-7,7-dioxido-4H-thieno[2,3-b]thiopyran-4-yl]; C10H14N2O5S3 (4S)-4-Acetamide-5,6-Dihydro-6-Methyl-2-Sulfonamide-Thio[2,3-B]Thiopyran7,7Dioxide 147-1; (4S-trans)-N-[2-(aminosulfonyl)-5,6-dihydro-6-methyl-7; (4S)-4-Acetamido-5,6-dihydro-6-methyl-2-sulfonamide-thieno[2,3-b]thiopyran 7,7-dioxide; (4S,6S)-4-(acetyl amino)-5,6-dihydro-6-methyl-4H-thieno[2,3]thiopyran-2-sulfonamide-7,7-dioxide; N-[(4S,6S)-6-Methyl-7,7-dioxo-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]; 4-(Acetamido)-5,6-dihydro-(S)-6-methyl- 4H-thieno [2,3-b]thiopyran-2- sulphonamide 7,7-dioxide; (4S)-4-Acetamide-5,6-Dihydro-6-Methyl-2-Sulfonamide-Thio[2,3-B]Thiopyran7,7Dioxide; Dorzolamide Impurity 5; (4S)-4-Acetamide-5,6-Dihydro-6-Methyl-2-Sulfonamide-Thio[2,3; N-[(4s,6s)-6-methyl-7,7-dioxo-2-sulfamoyl-5,6-dihydro-1H-thieno[2,3-b]thiopyran-4-yl]acetamide; (4S-trans)-N-[2-(aminosulfonyl)-5,6-dihydro-6-methyl-7,7-dioxido-4H-thieno-[2,3-b] thiopyran-4-yl]-acetamide; (4-trans)-N-[2-(Aminosulfonyl)-5,6-dihydro-6-methyl-7,7-dioxido-4H-thieno-[2,3-b]thiopyran-4-yl]-Acetamide; Acetamide,N-[2-(aminosulfonyl)-5,6-dihydro-6-methyl-7,7-dioxido-4H-thieno-[2,3-b] thiopyran-4-yl]-,(4S-trans); (4S-TRANS)-N-[2-(AMINOSULFONYL)-5,6-DIHYDRO-6-METHYL-7,7-DIOXIDE-4H-THIENO-[2,3-B]THIOPYRAN-4-YL]-ACETAMIDE; Dorzolamide N-Acetyl Analog; N-[(4S,6S)-6-METHYL-7,7-DIOXO-2-SULFAMOYL-5,6-DIHYDRO-4H-THIENO[2,3-B]THIOPYRAN-4-YL]ACETAMIDE

物化性质

• 密度: 1.62
• 分子式: C₁₀H₁₄N₂O₅S₃
• 分子量: 338.42400
• 精确质量: 338.00600
• PSA: 168.40000
• LogP: 3.39140
• 外观性状: 粉末
• 折射率: 1.647
• 储存条件: 2-8℃，惰性气体，避光

安全

• 危害码 (欧洲): Xi

合成路线

147086-79-1 ~% 147200-03-1 147128-79-8

文献：WO2014/5943 A1, ;

1083006-59-0 ~% 147200-03-1 147128-79-8

文献：WO2014/5943 A1, ;

1383784-43-7 ~% 147200-03-1 147128-79-8

文献：WO2014/5943 A1, ;

154716-03-7 ~% 147200-03-1 147128-79-8

文献：WO2014/5943 A1, ;

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