252990-05-9

• 常用中文名：(R)-1-Boc-2-哌嗪甲酸甲酯
• 常用英文名：Methyl (R)-1-Boc-piperazine-2-carboxylate
• CAS号：252990-05-9
• 分子式：C₁₁H₂₀N₂O₄
• 分子量：244.288
• 相关类别： 生物化工 氨基酸及其衍生物 BOC-氨基酸
• 发布时间：2018-12-16 10:07:56
• 更新时间：2026-07-01 13:54:48

名称

• 中文名: (R)-1-Boc-2-哌嗪甲酸甲酯
• 英文名: 1-O-tert-butyl 2-O-methyl (2R)-piperazine-1,2-dicarboxylate
• 中文别名: R-1-BOC-2-甲酸甲酯哌嗪; (R)-1-N-BOC-2-哌嗪甲酸甲酯; R-1-BOC-2-哌嗪甲酸甲酯游离不稳定; (R)-N-BOC-2-哌嗪甲酸甲酯; 1-叔-丁基 2-甲基 (2R)-哌嗪-1,2-二甲酸基酯; R-1-BOC-哌嗪-2-羧酸甲脂; (R)-哌嗪-1,2-二甲酸-1-叔丁酯-2-甲酯; (R)-1-N-叔丁氧羰基哌嗪-2-甲酸甲酯; (R)-1-BOC-2-哌嗪甲酸甲酯; (R)-1-B0C-2-哌嗉甲酸甲酯; (R)-1-BOC-哌嗪-2-甲酸甲酯; 1-(叔丁基)2-甲基(R)-哌嗪-1,2-二羧酸酯; (R)-1-N-BOC-哌嗪-2-甲酸甲酯; (R)-N-1-Boc-2-哌嗪甲酸甲酯
• 英文别名: methyl 1-N-Boc-(R)-(+)-piperazine-2-carboxylate; Piperazine-1,2-dicboxylic acid 1-tert-butyl ester 2-methyl ester; MFCD04115327; 1-tert-butyl ester 2-methyl ester; (R)-N-Boc-piperazine-2-cboxylic acid; (R)-1-N-Boc-piperazine-2-carboxylic acid methyl ester; (r)-1-tert-butyl 2-methyl piperazine-1,2-dicarboxylate; (R)-N-Boc-piperazine-2-carboxylic acid methyl ester; REF DUPL: (R)-1-N-Boc-piperazine-2-cboxylic acid methyl ester; 1,2-Piperazinedicarboxylic acid, 1-(1,1-dimethylethyl) 2-methyl ester; 1-tert-butyl 2-methyl-(2R)-piperazine-1,2-dicarboxylate; Piperazine-1,2-dicboxylic acid; (R)-1-N-Boc-piperazine-2-cboxylic acid methyl ester, min; (R)-1-N-Boc-piperazine-2-cboxylic; (R)-1-Boc-Piperazine-2-cboxylic acid methyl ester; [(2-N-BOC)PIPERAZINE(2R)COOH]-OME; 2-Methyl 1-(2-methyl-2-propanyl) 1,2-piperazinedicarboxylate; 1-(1,1-Dimethylethyl) 2-methyl (2R)-1,2-piperazinedicboxylate; 1-tert-Butyl-2-methylpiperazin-1,2-dicarboxylat; 2-Methyl 1-(2-methyl-2-propanyl) (2R)-1,2-piperazinedicarboxylate; (R)-N-Boc-piperazine-2-cboxylic acid methyl ester //BP; 1-(tert-butyl) 2-methyl (R)-piperazine-1,2-dicboxylate; (R)-Piperazine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester; (R)-1-TERT-BUTYL 2-METHYL PIPERAZINE-1,2-DICBOXYLATE; (R)-1-N-Boc-Piperazine-2-cboxylic acid Methyl ester; 1,2-Piperazinedicboxylic acid, 1-(1,1-dimethylethyl) 2-methyl ester, (2R); 1-O-tert-butyl 2-O-methyl (2R)-piperazine-1,2-dicboxylate; Methyl (R)-1-N-Boc-piperazine-2-cboxylate; (R)-Piperazine-1,2-dicboxylic acid 1-tert-butyl ester 2-methyl ester (R)-1-Boc-piperazine-2-cboxylic acid methyl ester; Methyl (R)-1-Boc-piperazine-2-cboxylate; (R)-PIPERAZINE-1,2-DICBOXYLIC ACID 1-TERT-BUTYL ESTER 2-METHYL ESTER; (R)-N-Boc-piperazine-2-cboxylic acid methyl ester; N-boc-piperazine-2-carboxylic acid methyl ester; 1-tert-butyl 2-Methyl (2R)-piperazine-1,2-dicboxylate; 1-tert-Butyl 2-methyl piperazine-1,2-dicarboxylate

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 321.3±37.0 °C at 760 mmHg
• 分子式: C₁₁H₂₀N₂O₄
• 分子量: 244.288
• 闪点: 148.1±26.5 °C
• 精确质量: 244.142303
• PSA: 67.87000
• LogP: 0.73
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.472
• 储存条件: 室温，干燥

安全

• 海关编码: 2933599090

合成路线

278788-60-6 18107-18-1 ~47% 252990-05-9

文献：ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2005/26152 A1, 2005 ; Location in patent: Page/Page column 136 ; WO 2005/026152 A1

上下游产品

上游产品  2
278788-60-6 18107-18-1
下游产品  1
169448-87-7

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%