84044-26-8

• 常用中文名：1-Methyl-7-chloro-5-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin- 2-one
• 常用英文名：1-Methyl-7-chloro-5-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin- 2-one
• CAS号：84044-26-8
• 分子式：C₁₇H₁₅ClN₄O₂
• 分子量：342.78000
• 发布时间：2016-03-25 15:15:37
• 更新时间：2025-09-13 17:27:20

名称

• 英文名: 1-Methyl-7-chloro-5-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin- 2-one
• 英文别名: 1-Methyl-7-chloro-5-phenyl-3-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin-2-one; 1-Methyl-7-chloro-5-phenyl-3-acetylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin-2-one

物化性质

• 密度: 1.32g/cm3
• 沸点: 628ºC at 760 mmHg
• 分子式: C₁₇H₁₅ClN₄O₂
• 分子量: 342.78000
• 闪点: 333.6ºC
• 精确质量: 342.08800
• PSA: 73.80000
• LogP: 2.28000
• 折射率: 1.665

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DG5105000 CHEMICAL NAME : Benzoic acid, 2-(7-chloro-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1, 4-benzodiazepin-3-yl) hydrazide CAS REGISTRY NUMBER : 84044-26-8 LAST UPDATED : 199803 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C23-H19-Cl-N4-O2 MOLECULAR WEIGHT : 418.91 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Behavioral - anticonvulsant Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,617,1982

合成路线

613-94-5 23433-96-7 ~84% 84044-26-8

文献：Gorbunov, V. I.; Gorbunova, S. M.; Khlienko, Zh. N.; Kurilenko, V. M. Pharmaceutical Chemistry Journal, 1982 , vol. 16, # 8 p. 617 - 622 Khimiko-Farmatsevticheskii Zhurnal, 1982 , vol. 16, # 8 p. 951 - 956

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