1187-00-4

• 常用中文名：甘露醇二磺酸酯
• 常用英文名：D-Mannitol,1,6-dimethanesulfonate
• CAS号：1187-00-4
• 分子式：C₈H₁₈O₁₀S₂
• 分子量：338.35300
• 发布时间：2016-07-01 01:03:09
• 更新时间：2024-01-11 22:32:26

名称

• 中文名: 甘露醇二磺酸酯
• 英文名: D-Mannitol,1,6-dimethanesulfonate
• 英文别名: O1,O6-Dimethansulfonyl-D-mannit; Mannogranol; D-Mannitol busulphan; D-Mannitol busulfan; O1,O6-bis-methanesulfonyl-D-mannitol; 1,6-Bis-methansulfonyl-D-mannit; MANNITOL,1,6-DIMETHYLSULPHONATE,D; 1,6-Di-O-methansulfonyl-D-mannitol; 2511 C. B.; O1,O6-Bis-methansulfonyl-D-mannit; 1,6-Dimethanesulfonate-D-mannitol; 1,6-Bis-methansulfonyloxy-D-manno-hexan-2,3,4,5-tetraol; 1,6-Dimesyl-D-mannitol; 1,6-Di-O-methansulfonyl-D-mannit; 1,6-Dimethanesulfonoxy-D-mannitol

物化性质

• 密度: 1.635g/cm3
• 沸点: 721.3ºC at 760 mmHg
• 熔点: 134-136 °C
• 分子式: C₈H₁₈O₁₀S₂
• 分子量: 338.35300
• 闪点: 390ºC
• 精确质量: 338.03400
• PSA: 184.42000
• 蒸汽压: 5.01E-24mmHg at 25°C
• 折射率: 1.553
• 储存条件:

  1.库房通风低温干燥；与食品原料分开存放。

• 稳定性:

  1.中毒，可燃，受热分解有毒硫氧化物烟雾。

• 分子结构:

  1、 摩尔折射率：66.25

  2、 摩尔体积（cm³/mol）：206.9

  3、 等张比容（90.2K）：612.5

  4、 表面张力（dyne/cm）：76.8

  5、 极化率（10-24cm3）：26.26

毒性和生态

毒理学数据: 腹腔-大鼠 LA50: 2000 毫克/公斤; 口服-小鼠 LD50: 6000 毫克/公斤 CHEMICAL IDENTIFICATION RTECS NUMBER : OP2975000 CHEMICAL NAME : Mannitol, 1,6-dimethanesulfonate, D- CAS REGISTRY NUMBER : 1187-00-4 LAST UPDATED : 199707 DATA ITEMS CITED : 12 MOLECULAR FORMULA : C8-H18-O10-S2 MOLECULAR WEIGHT : 338.38 WISWESSER LINE NOTATION : WS1&O1YQYQYQYQ1OSW1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Blood - normocytic anemia Blood - thrombocytopenia TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 6 gm/kg TOXIC EFFECTS : Tumorigenic - protects against induction of experimental tumors TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2500 mg/kg TOXIC EFFECTS : Tumorigenic - protects against induction of experimental tumors TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 135 mg/kg TOXIC EFFECTS : Blood - leukopenia Blood - agranulocytosis Blood - other changes TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Primate - monkey DOSE/DURATION : 135 mg/kg TOXIC EFFECTS : Blood - leukopenia Blood - agranulocytosis Blood - other changes TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1000 mg/kg/4W TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors TYPE OF TEST : Specific locus test TYPE OF TEST : Cytogenetic analysis TYPE OF TEST : Sex chromosome loss and nondisjunction TYPE OF TEST : Sex chromosome loss and nondisjunction MUTATION DATA TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - rabbit Bone marrow DOSE/DURATION : 1700 umol/L REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 25,1705,1976

安全

• 海关编码: 2905499000

海关

海关编码	2905499000
中文概述	2905499000 其他多元醇。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2905499000 other polyhydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%