168626-74-2

• 常用中文名：4-(2-苯基苯甲酰胺基)苯甲酸
• 常用英文名：4-[(2-Biphenylylcarbonyl)amino]benzoic acid
• CAS号：168626-74-2
• 分子式：C₂₀H₁₅NO₃
• 分子量：317.338
• 发布时间：2018-10-08 11:41:23
• 更新时间：2026-08-02 17:32:35

名称

• 中文名: 4-(2-苯基苯甲酰胺基)苯甲酸
• 英文名: 4-[(2-phenylbenzoyl)amino]benzoic acid
• 中文别名: 盐酸康伐普坦杂质A; 4-[(联苯-2-羰基)氨基]苯甲酸; 4-[(联苯-2-基羰基)氨基]苯甲酸; 盐酸西尼伐普坦杂质A; 4-(联苯-2-酰胺基)苯甲酸; 用作盐酸考尼伐坦中间体; 考尼伐坦杂质3; 考尼伐坦杂质D; 3'-甲酰胺-[1,1':4',1''-三联苯]-2-羧酸
• 英文别名: Conivaptan impurity D; Benzoic acid, 4-[([1,1'-biphenyl]-2-ylcbonyl)amino]; 4-([1,1'-Biphenyl]-2-ylcboxamido)benzoic acid; Conivaptan Impurity 1; 4-[([1,1'-Biphenyl]-2-carbonyl)amino]benzoic Acid; 4-[(2-phenylphenyl)carbonylamino]benzoic acid; 4-([1,1'-biphenyl]-2-cboxamido)benzoic acid; 4-[(2-Biphenylcbonyl)amino]benzoic acid; Conivaptan intermediate; ethyl 4-(2-phenylbenzoyl)aminobenzoic acid; 3'-Formamido-[1,1':4',1''-terphenyl]-2-cboxylic acid; 4-[(biphenyl-2-ylcarbonyl)amino]benzoic acid; Conivaptan-4; 4-[(biphenyl-2-carbonyl)amino]benzoic acid; 4-(2-Phenylbenzamido)benzoic acid; 4-([1,1'-biphenyl]-2-ylcarboxamido)benzoic acid; 4-[([1,1'-biphenyl]-2-ylcbonyl)amino]Benzoic acid; 4-[(2-Biphenylylcbonyl)amino]benzoic acid; 4-[(Biphenyl-2-ylcbonyl)amino]benzoic acid; Conivaptan hydrochloride Impurity D; 4-[[oxo-(2-phenylphenyl)methyl]amino]benzoic acid; 4-[([1,1'-biphenyl]-2-ylcarbonyl)amino]benzoic acid

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 474.5±38.0 °C at 760 mmHg
• 熔点: 246-248ºC
• 分子式: C₂₀H₁₅NO₃
• 分子量: 317.338
• 闪点: 240.8±26.8 °C
• 精确质量: 317.105194
• PSA: 66.40000
• LogP: 4.19
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.674

安全

• 海关编码: 2924299090

合成路线

180340-04-9 ~% 168626-74-2

文献：US2004/259857 A1, ; Page 20 ;

217495-89-1 ~86% 168626-74-2

文献：Matsuhisa, Akira; Koshio, Hiroyuki; Sakamoto, Kenichiro; Taniguchi, Nobuaki; Yatsu, Takeyuki; Tanaka, Akihiro Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 10 p. 1566 - 1579

947-84-2 ~% 168626-74-2

文献：Chemical and Pharmaceutical Bulletin, , vol. 46, # 10 p. 1566 - 1579

14002-52-9 150-13-0 ~% 168626-74-2

文献：Tsunoda, Takashi; Yamazaki, Atsuki; Mase, Toshiyasu; Sakamoto, Shuichi Organic Process Research and Development, 2005 , vol. 9, # 5 p. 593 - 598

94-09-7 ~% 168626-74-2

文献：Chemical and Pharmaceutical Bulletin, , vol. 46, # 10 p. 1566 - 1579

619-45-4 ~% 168626-74-2

文献：Journal of Medicinal Chemistry, , vol. 55, # 20 p. 8588 - 8602

上下游产品

上游产品  6
217495-89-1 947-84-2 14002-52-9 150-13-0
94-09-7 619-45-4
下游产品  1
180340-05-0

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%