71576-41-5

• 常用中文名：Aptazapine
• 常用英文名：Aptazapine
• CAS号：71576-41-5
• 分子式：C₂₀H₂₃N₃O₄
• 分子量：369.41400
• 发布时间：2016-08-28 03:42:41
• 更新时间：2024-10-02 20:46:35

名称

• 英文名: aptazapine maleate
• 英文别名: 2H,10H-Pyrazino(1,2-a)pyrrolo(2,1-c)(1,4)benzodiazepine,1,3,4,14b-tetrahydro-2-methyl-,(+-)-,(Z)-2-butenedioate (1:1); CGS-7525A; Aptazapine maleate (USAN); C16H19N3.C4H4O4

物化性质

• 分子式: C₂₀H₂₃N₃O₄
• 分子量: 369.41400
• 精确质量: 369.16900
• PSA: 86.01000
• LogP: 2.05760

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UQ4730325 CAS REGISTRY NUMBER : 71576-41-5 LAST UPDATED : 199512 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C16-H19-N3.C4-H4-O4 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 43680 mg/kg/2Y-I TOXIC EFFECTS : Cardiac - other changes Endocrine - other changes Kidney, Ureter, Bladder - other changes REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,46,1986 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 32760 mg/kg/78W-I TOXIC EFFECTS : Cardiac - other changes Liver - other changes Kidney, Ureter, Bladder - other changes REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,46,1986 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1092 mg/kg/52W-I TOXIC EFFECTS : Brain and Coverings - other degenerative changes Liver - other changes Kidney, Ureter, Bladder - other changes REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,46,1986