849217-60-3

• 常用中文名：N-(4-氟苯基)-N-(4-羟基苯基)环丙烷-1,1-二羧酰胺
• 常用英文名：N-(4-Fluorophenyl)-N'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
• CAS号：849217-60-3
• 分子式：C₁₇H₁₅FN₂O₃
• 分子量：314.31100
• 发布时间：2018-12-31 11:30:52
• 更新时间：2026-07-04 14:23:55

名称

• 中文名: N-(4-氟苯基)-n-(4-羟基苯基)环丙烷-1,1-二羧酰胺
• 英文名: N-(4-Fluorophenyl)-N'-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide
• 中文别名: 卡博替尼杂质7; 果酸卡博替尼Int2-Imp2; N-(4-氟苯基)-N-(4-羟基苯基)环丙烷-1,1-二羧酰胺(卡博替尼杂质); 环丙烷-1,1-二甲酸 N-(4-氟苯基)酰胺 N'-(4-羟基苯基)酰胺; 卡博替尼杂质82
• 英文别名: N-(4-Fluorophenyl)-N'-(4-hydroxyphenyl)cyclopropane-1,1-dicboxamide; 1,1-Cyclopropanedicboxamide, N-(4-fluorophenyl)-N'-(4-hydr; 1-(4-fluorophenyl)-N1-(4-hydroxyphenyl)cyclopropane-1,1-dicboxamide; 1,1-Cyclopropanedicboxamide, N-(4-fluorophenyl)-N'-(4-hydroxyphenyl); N-(4-Fluorophenyl)-N'-(4-hydroxyphenyl)cyclopropane-1,1-dicboxamide(CabozantinibImpurity); 1-N'-(4-fluorophenyl)-1-N-(4-hydroxyphenyl)cyclopropane-1,1-dicboxamide; 1-N'-(4-fluorophenyl)-1-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide; Cabozantinib Impurity 82; N-(4-fluorophenyl)-N-(4-hydroxyphenyl)-1,1-Cyclopropanedicboxamide; N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicboxamide; Cabotinib Impurity 7; N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicboxamide ISO 9001：2015 REACH; N'1-(4-fluorophenyl)-N1-(4-hydroxyphenyl)cyclopropane-1,1-dicboxamide; Cyclopropane-1,1-dicboxylic acid N-(4-fluorophenyl)amide N'-(4-hydroxyphenyl)amide; Cabozantinib impurities5; cyclopropane-1,1-dicboxylic acid (4-fluoro-phenyl)-amide (4-hydroxy-phenyl)-amide

物化性质

• 分子式: C₁₇H₁₅FN₂O₃
• 分子量: 314.31100
• 精确质量: 314.10700
• PSA: 78.43000
• LogP: 3.03470
• 储存条件: 室温，干燥

安全

• 危害码 (欧洲): Xi
• 海关编码: 2924299090

合成路线

849217-59-0 ~92% 849217-60-3

文献：EXELIXIS, INC. Patent: WO2005/30140 A2, 2005 ; Location in patent: Page/Page column 205 ; WO 2005/030140 A2

849217-48-7 123-30-8 ~85% 849217-60-3

文献：EXELIXIS, INC. Patent: WO2005/30140 A2, 2005 ; Location in patent: Page/Page column 205 ; WO 2005/030140 A2

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%