206446-49-3

• 常用中文名：3',4',5',6'-四氢-2'H-[2,4'-联吡啶]-1'-羧酸叔丁基酯
• 常用英文名：3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-carboxylic acid tert-butyl ester
• CAS号：206446-49-3
• 分子式：C₁₅H₂₂N₂O₂
• 分子量：262.34700
• 发布时间：2019-01-21 12:28:17
• 更新时间：2024-01-15 22:13:30

名称

• 中文名: 4-(吡啶-2-基)哌啶-1-羧酸叔丁酯
• 英文名: tert-butyl 4-pyridin-2-ylpiperidine-1-carboxylate
• 英文别名: tert-butyl 4-pyridin-2-yl-piperidine-1-carboxylate

物化性质

• 密度: 1.083±0.06 g/cm3(Predicted)
• 分子式: C₁₅H₂₂N₂O₂
• 分子量: 262.34700
• 精确质量: 262.16800
• PSA: 42.43000
• LogP: 3.13400
• 外观性状: 无色油
• 储存条件: 室温， 密封， 干燥

安全

• 危害码 (欧洲): Xn
• 海关编码: 2933990090

合成路线

90606-77-2 ~96% 206446-49-3

文献：Abbott Laboratories Patent: WO2003/101994 A1, 2003 ; Location in patent: Page 105 ; WO 03/101994 A1

109-04-6 301673-14-3 ~22% 206446-49-3

文献：PFIZER LIMITED; PFIZER INC. Patent: WO2006/21882 A1, 2006 ; Location in patent: Page/Page column 28 ; WO 2006/021882 A1

109384-19-2 ~% 206446-49-3

文献：Billotte Synlett, 1998 , # 4 p. 379 - 380

138647-49-1 ~% 206446-49-3

文献：Patel, Meena V.; Kolasa, Teodozyj; Mortell, Kathleen; Matulenko, Mark A.; Hakeem, Ahmed A.; Rohde, Jeffrey J.; Nelson, Sherry L.; Cowart, Marlon D.; Nakane, Masaki; Miller, Loan N.; Uchic, Marie E.; Terranova, Marc A.; El-Kouhen, Odile F.; Donnelly-Roberts, Diana L.; Namovic, Marian T.; Hollingsworth, Peter R.; Chang, Renjie; Martino, Brenda R.; Wetter, Jill M.; Marsh, Kennan C.; Martin, Ruth; Darbyshire, John F.; Gintant, Gary; Hsieh, Gin C.; Moreland, Robert B.; Sullivan, James P.; Brioni, Jorge D.; Stewart, Andrew O. Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7450 - 7465

5382-16-1 ~% 206446-49-3

文献：Billotte Synlett, 1998 , # 4 p. 379 - 380

24424-99-5 ~% 206446-49-3

文献：Billotte Synlett, 1998 , # 4 p. 379 - 380

79099-07-3 ~% 206446-49-3

文献：Patel, Meena V.; Kolasa, Teodozyj; Mortell, Kathleen; Matulenko, Mark A.; Hakeem, Ahmed A.; Rohde, Jeffrey J.; Nelson, Sherry L.; Cowart, Marlon D.; Nakane, Masaki; Miller, Loan N.; Uchic, Marie E.; Terranova, Marc A.; El-Kouhen, Odile F.; Donnelly-Roberts, Diana L.; Namovic, Marian T.; Hollingsworth, Peter R.; Chang, Renjie; Martino, Brenda R.; Wetter, Jill M.; Marsh, Kennan C.; Martin, Ruth; Darbyshire, John F.; Gintant, Gary; Hsieh, Gin C.; Moreland, Robert B.; Sullivan, James P.; Brioni, Jorge D.; Stewart, Andrew O. Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7450 - 7465

上下游产品

上游产品  8
90606-77-2 109-04-6 301673-14-3 109384-19-2
79099-07-3 138647-49-1 5382-16-1 24424-99-5
下游产品  3
143924-45-2 30532-37-7 630119-43-6

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%