78756-03-3

• 常用中文名：5-甲基-6-氧代-5,6-乙基二氢-4H-苯并[f]咪唑[1,5-a] [1,4]二氮杂-3-羧酸酯-d3乙酯
• 常用英文名：Ro 14-7437
• CAS号：78756-03-3
• 分子式：C₁₅H₁₅N₃O₃
• 分子量：285.30
• 相关类别： 研究领域 神经疾病
• 发布时间：2017-08-20 12:40:31
• 更新时间：2026-06-29 17:23:12
• Ro 14-7437 是一种强效、选择性的 Midazolam 增强拮抗剂。

名称

• 中文名: 5-甲基-6-氧代-5,6-乙基二氢-4H-苯并[f]咪唑[1,5-a] [1,4]二氮杂-3-羧酸酯-d3乙酯
• 英文名: ethyl 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
• 中文别名: 氟马西尼杂质5(氟马西尼杂质E); 氟马西尼杂质E
• 英文别名: Flumazenil Related Compound C; Ro 14 7437,Ro; ethyl 5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzo; 5,6-Dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazine-3-cboxylic acid ethyl ester; ethyl 5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazine-3-cboxylate; ethyl 5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazine-3-cboxylate; Flumazenil Impurity 5(Flumazenil Impurity E); 4H-Imidazo[1,5-a][1,4] benzodiazepine-3-carboxylic acid, 5,6-dihydro-5-methyl-6-oxo-, ethyl ester; Ethyl 5-Methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate; Ro 7; Ethyl 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate; Flumazenil Impurity E; 4H-IMidazo[1,5-a][1,4] benzodiazine-3-cboxylic acid, 5,6-dihydro-5-Methyl-6 -oxo-, ethyl ester; Ethyl 5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a) (1,4)-benzodiazepine-3-carboxylate; ethyl 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][ 1,4]benzodiazepine-3-carboxylate; Imp. E:ethyl 5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazine-3-cboxylate

物化性质

• 分子式: C₁₅H₁₅N₃O₃
• 分子量: 285.30
• 精确质量: 285.11100
• PSA: 64.43000
• LogP: 1.57250

生物活性

• 描述: Ro 14-7437 是一种强效、选择性的 Midazolam 增强拮抗剂。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Nistri A,et al. Potentiating action of midazolam on GABA-mediated responses and its antagonism by Ro 14-7437 in the frog spinal cord. Neurosci Lett. 1983 Aug 29;39(2):199-204.

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