1300-21-6

• 常用中文名：二氯乙烷
• 常用英文名：Dichloroethane
• CAS号：1300-21-6
• 分子式：C₂H₄Cl₂
• 分子量：98.959
• 相关类别： 有机原料 烃类化合物及其衍生物 烃类卤化物
• 发布时间：2018-02-05 08:00:00
• 更新时间：2024-01-04 17:49:55
• 主要用作氯乙烯、乙二醇、乙二酸、乙二胺、四乙基铅、多乙烯多胺及联苯甲酰的原料。也用作油脂、树脂、橡胶的溶剂，干洗剂，农药除早菊素、咖啡因、维生素、激素的萃取剂，湿润剂，浸透剂，石油脱蜡，抗震剂，还用于农药制造以及药物灭虫宁、哌哔嗪的原料。在农业上可用作粮?

名称

• 中文名: 1,1-二氯乙烷
• 英文名: Dichloroethane
• 中文别名: 乙撑二氯; 二氯乙烷

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 83.5±0.0 °C at 760 mmHg
• 熔点: -35ºC
• 分子式: C₂H₄Cl₂
• 分子量: 98.959
• 闪点: 15.6±0.0 °C
• 精确质量: 97.969009
• LogP: 1.41
• 蒸汽压: 83.9±0.1 mmHg at 25°C
• 折射率: 1.413

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KH9800000 CHEMICAL NAME : Ethane, dichloro- CAS REGISTRY NUMBER : 1300-21-6 BEILSTEIN REFERENCE NO. : 0605264 LAST UPDATED : 199710 DATA ITEMS CITED : 16 MOLECULAR FORMULA : C2-H4-Cl2 MOLECULAR WEIGHT : 98.96 WISWESSER LINE NOTATION : G2G HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1120 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 32(3),349,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 625 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 32(3),349,1967 TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 10 gm/m3 TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 20(8),19,1955 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 18(6),53,1974 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 3890 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 3/23/1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(10),25,1988 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 5 gm/m3 TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(10),25,1988 ** REPRODUCTIVE DATA ** TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation DOSE : 15 mg/m3/4H SEX/DURATION : female 16 week(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 41(6),100,1976 TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation DOSE : 57 mg/m3/4H SEX/DURATION : female 26 week(s) pre-mating female 1-22 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - stillbirth Reproductive - Effects on Newborn - live birth index (measured after birth) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 19(7),20,1975 TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation DOSE : 15 mg/m3/4H SEX/DURATION : female 96 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - menstrual cycle changes or disorders REFERENCE : AKGIAO Akushcherstvo i Ginekologiya (Moscow). (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1936- Volume(issue)/page/year: 53(2),57,1977 TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation DOSE : 15 mg/m3/4H SEX/DURATION : female 96 day(s) pre-mating female 1-18 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetal death REFERENCE : AKGIAO Akushcherstvo i Ginekologiya (Moscow). (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1936- Volume(issue)/page/year: 53(2),57,1977 TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation DOSE : 57 mg/m3/4H SEX/DURATION : female 22 week(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(7),25,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1086 No. of Facilities: 176 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 3200 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1086 No. of Facilities: 84 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 3207 (estimated) No. of Female Employees: 1149 (estimated)

安全

• 危害码 (欧洲): F:Flammable;T:Toxic;
• 风险声明 (欧洲): R11;R22;R36/37/38;R45
• 安全声明 (欧洲): S45-S53
• 危险品运输编码: UN 1184 3/PG 2
• 包装等级: II
• 海关编码: 2903150000

制备

1.乙烯与氯气直接合成法　以乙烯和氯气在1,2-二氯乙烷介质中进行氯化生成粗二氯乙烷及少量多氯化物，加碱闪蒸除去酸性物及部分高沸物，用水洗涤至中性，共沸脱水，精馏，得成品。2.乙烯氧氯化法乙烯直接与氯气氯化生成二氯乙烷。由二氯乙烷裂解制氯乙烯时回收的氯化氢和预热至150-200℃的含氧气体（空气）和乙烯，通过载于氧化铝上的氯化铜触媒，在压力0.0683-0.1033MPa；温度200-250℃下反应，粗产品经冷却（使大部分三氯乙醛和部分水冷凝）；加压；精制，得二氯乙烷产品。3.由石油裂解气或焦炉的乙烯直接氯化的方法。此外，在氯乙醇；环氧乙烷的生产中还副产有1,2-二氯乙烷。4.将工业品1,2-二氯乙烷是用浓硫酸洗至酸层无色，而后用5%的氢氧化钙溶液洗，再用水洗一次，分去水层。用无水氯化钙干燥后，进行精馏。1,2-二氯乙烷能与水形成共沸混合物，含有8.9%的水，共沸点7.7℃。利用此特性脱去大量的水后再进行干燥和蒸馏即得纯品1,2-二氯乙烷。5.将催化剂三氯化铁、氯化铜或氯化亚锑悬浮于二氯乙烷中作为反应介质，分别通入气体乙烯和氯气进行反应，控制反应温度为50～70℃，反应压力0.4～0.5 MPa：反应所得产物用水洗去氯化氢和催化剂，静置分层，分去水层，然后用1%～2%的氢氧化钠洗涤，分去水层后进行共沸精馏，蒸出的共沸物静置分去水层，干燥后，再精馏，即得1,2-二氯乙烷纯品。

海关

海关编码	2903150000
申报要素	品名, 成分含量, 用途
监管条件	A.入境货物通关单 B.出境货物通关单 X.有毒化学品环境管理放行通知单
检验检疫	R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验
Summary	2903150000 1,2-dichloroethane。supervision conditions:ABx(certificate of inspection for goods inward,certificate of inspection for goods outward,environment control release notice for poisonous chemicals)。VAT:17.0%。tax rebate rate:0.0%。MFN tarrif:5.5%。general tariff:30.0%