1008-95-3

• 常用中文名：4-(1,3-恶唑-5-基)苯胺
• 常用英文名：4-(1,3-Oxazol-5-yl)aniline
• CAS号：1008-95-3
• 分子式：C₉H₈N₂O
• 分子量：160.17300
• 发布时间：2018-06-10 21:33:12
• 更新时间：2024-01-11 21:11:31

名称

• 中文名: 4-(5-噁唑基)苯胺
• 英文名: 4-(5-Oxazolyl)aniline
• 中文别名: 4-(1,3-吡啶-5-）吲哚
• 英文别名: 4-(1,3-OXAZOL-5-YL)ANILINE; 4-(1,3-Oxazol-5-yl)aniline

物化性质

• 密度: 1.204g/cm3
• 沸点: 318.7ºC at 760mmHg
• 熔点: 150ºC
• 分子式: C₉H₈N₂O
• 分子量: 160.17300
• 闪点: 146.5ºC
• 精确质量: 160.06400
• PSA: 52.05000
• LogP: 2.50500
• 蒸汽压: 0.000356mmHg at 25°C
• 折射率: 1.599
• 储存条件: 室温，密封，干燥

MSDS

Name: 4-(1 3-Oxazol-5-yl)aniline tech Material Safety Data Sheet Synonym: CAS: 1008-95-3 Section 1 - Chemical Product MSDS Name:4-(1 3-Oxazol-5-yl)aniline tech Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 1008-95-3 4-(1,3-Oxazol-5-yl)aniline unlisted Hazard Symbols: None Listed. Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Not available. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 1008-95-3: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 148 - 150 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C9H8N2O Molecular Weight: 160.18 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 1008-95-3 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-(1,3-Oxazol-5-yl)aniline - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 1008-95-3: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 1008-95-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 1008-95-3 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26-36/37/39
• 海关编码: 2934999090

合成路线

1014-23-9 ~91% 1008-95-3

文献：F2G LTD Patent: WO2006/123145 A1, 2006 ; Location in patent: Page/Page column 66-67 ;

1014-23-9 7439-89-6 ~80% 1008-95-3

文献：Cell Therapeutics, Inc. Patent: US2004/204386 A1, 2004 ;

1186127-11-6 ~63% 1008-95-3

文献：Primas, Nicolas; Bouillon, Alexandre; Lancelot, Jean-Charles; Rault, Sylvain Tetrahedron, 2009 , vol. 65, # 32 p. 6348 - 6353

267648-15-7 ~% 1008-95-3

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 12 p. 2059 - 2063

5274-71-5 ~% 1008-95-3

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 12 p. 2059 - 2063

7745-93-9 ~% 1008-95-3

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 12 p. 2059 - 2063

470715-98-1 ~% 1008-95-3

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 12 p. 2059 - 2063

38622-91-2 555-16-8 ~% 1008-95-3

文献：US6344465 B1, ; Page column 17-18 ;

上下游产品

上游产品  7
1014-23-9 7439-89-6 1186127-11-6 5274-71-5
7745-93-9 38622-91-2 555-16-8
下游产品  0

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%