103249-79-2

• 常用中文名：4-甲基-2-苯基-5-嘧啶甲酸
• 常用英文名：4-METHYL-2-PHENYL-5-PYRIMIDINECARBOXYLIC ACID
• CAS号：103249-79-2
• 分子式：C₁₂H₁₀N₂O₂
• 分子量：214.22000
• 相关类别： 医药中间体 杂环化合物 嘧啶类化合物 苯基嘧啶
• 发布时间：2018-12-22 18:00:09
• 更新时间：2024-01-21 18:11:54
• 下载msds

名称

• 中文名: 4-甲基-2-苯基-5-嘧啶甲酸
• 英文名: 4-methyl-2-phenylpyrimidine-5-carboxylic acid
• 英文别名: 4-methyl-2-phenyl-5-pyrimidinecarboxylic acid; 2-Phenyl-4-methyl-5-pyrimidincarbonsaeure; 4-Methyl-2-phenylpyrimidine-5-carboxylic acid; 5-Pyrimidinecarboxylicacid,4-methyl-2-phenyl; 2-Phenyl-4-methylpyrimidin-5-carboxylic acid; 4-methyl-2-phenyl-pyrimidine-5-carboxylic acid; 4-Methyl-2-phenyl-pyrimidin-5-carbonsaeure

物化性质

• 密度: 1.26g/cm3
• 沸点: 306.6ºC at 760mmHg
• 熔点: 247-248ºC
• 分子式: C₁₂H₁₀N₂O₂
• 分子量: 214.22000
• 闪点: 139.2ºC
• 精确质量: 214.07400
• PSA: 63.08000
• LogP: 2.15020
• 蒸汽压: 0.000332mmHg at 25°C
• 折射率: 1.608

MSDS

Name: 4-Methyl-2-phenyl-5-pyrimidinecarboxylic acid 97% Material Safety Data Sheet Synonym: CAS: 103249-79-2 Section 1 - Chemical Product MSDS Name:4-Methyl-2-phenyl-5-pyrimidinecarboxylic acid 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 103249-79-2 4-Methyl-2-phenyl-5-pyrimidinecarboxyl 97% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 103249-79-2: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 247 - 248 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C12H10N2O2 Molecular Weight: 214.22 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, bases. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 103249-79-2 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-Methyl-2-phenyl-5-pyrimidinecarboxylic acid - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 103249-79-2: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 103249-79-2 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 103249-79-2 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26
• 海关编码: 2933599090

合成路线

773134-16-0 ~98% 103249-79-2

文献：Journal of Combinatorial Chemistry, , vol. 12, # 3 p. 327 - 331

70733-12-9 ~90% 103249-79-2

文献：Journal of Heterocyclic Chemistry, , vol. 27, # 2 p. 295 - 305

134653-70-6 ~% 103249-79-2

文献：Journal of Heterocyclic Chemistry, , vol. 27, # 2 p. 295 - 305

618-39-3 ~% 103249-79-2

文献：Journal of Heterocyclic Chemistry, , vol. 27, # 2 p. 295 - 305

66373-27-1 ~% 103249-79-2

文献：Journal of the Chemical Society, , vol. 128, p. 2181

上下游产品

上游产品  5
773134-16-0 70733-12-9 134653-70-6 618-39-3
66373-27-1
下游产品  1
34771-48-7

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%