146-17-8

• 常用中文名：2,6-蒽二酚
• 常用英文名：Riboflavine phosphate
• CAS号：146-17-8
• 分子式：C₁₇H₂₁N₄O₉P
• 分子量：456.34400
• 相关类别： 研究领域 其他
• 发布时间：2018-03-10 08:00:00
• 更新时间：2026-07-02 13:08:24
• Riboflavine phosphate 是一种非常有效的 NAD+ 回收剂。

名称

• 中文名: 2,6-蒽二酚
• 英文名: fmn
• 中文别名: 黃酚; 核[糖]黃素磷酸鈉鹽; Β黄素单核苷酸
• 英文别名: Riboflavine phosphate (Riboflavine 5'-phosphate); Riboflavine 5'-(dihydrogen phosphate); 7,8-Dimethyl-10-ribitylisoalloxazine Phosphate; Riboflavine 5'-phosphate; EINECS 205-664-7; riboflavinemonophosphate; vitamin B2 phosphate; RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE(RG); riboflavin5’-monophosphate; Riboflavine 5'-monophosphate; 7,8-Dimethyl-10-(d-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine 5'-(dihydrogenphosphate); Riboflavine dihydrogen phosphate; riboflavine5’-monophosphate; Riboflavum 5 -dihydrophosphate; riboflavine5’-phosphate; Riboflavine phosphate (Synonyms: Riboflavine 5'-phosphate); Riboflavin 5''-monophosphoric acid; 5’-(dihydrogenphosphate)-riboflavi; FLAVIN MONONUCLEOTIDE; riboflavinmononucleotide; riboflavinhosphate; flavinemononucleotide; Riboflavin phosphate; sodium riboflavine monophosphate; RIBOFLAVIN5PHOSPHATEESTER; Riboflavin 5'-(dihydrogen phosphate); Riboflavin-5'-phosphate na; (-)-Riboflavin 5-phosphate; riboflavinphosphate; Flanin; Flavol; RIBOFLAVIN 5′-MONPHOSPHATE; 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-5-O-phosphonopentitol; riboflavin mononucleotide; Riboflavin 5'-monophosphate; flavin mononucleotide phosphate; Riboflavin Mononucleotide; 5'-(Dihydrogen Phosphate)riboflavin; riboflavin-5'-monophosphate; Flavine mononucleotide; Riboflavin monophosphate; RIBOFLAVIN-5'-PHOSPHATE; Riboflavine monophosphate; riboflavinedihydrogenphosphate

物化性质

• 密度: 1.83g/cm3
• 熔点: 195°C
• 分子式: C₁₇H₂₁N₄O₉P
• 分子量: 456.34400
• 精确质量: 456.10500
• PSA: 217.90000
• 外观性状: 黄色至橙色结晶粉末
• 折射率: 1.747
• 储存条件: -20°C
• 分子结构:

  1、 摩尔折射率：101.05

  2、 摩尔体积（cm³/mol）：248.8

  3、 等张比容（90.2K）：761.5

  4、 表面张力（dyne/cm）：87.6

  5、 极化率（10-24cm3）：40.06

生物活性

• 描述: Riboflavine phosphate 是一种非常有效的 NAD+ 回收剂。
• 相关类别:
  天然产物 >> 酸和醛
  研究领域 >> 其他
• 靶点:

  Human Endogenous Metabolite

• 体外研究: 核黄素磷酸盐(黄素单核苷酸,FMN)显然是一种非常有效的NAD +再循环剂,具有良好的环己酮产物收率,同时常规达到高水平的NAP转换[1]。
• 参考文献:

  [1]. J. Bryan Jones, et al. Nicotinamide coenzyme regeneration. Flavin mononucleotide (riboflavin phosphate) as an efficient, economical, and enzyme-compatible recycling agent. Can J Chem. 1976, 54(19): 2969-2973,

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VJ1350000 CHEMICAL NAME : Riboflavin, 5'-(dihydrogenphosphate)- CAS REGISTRY NUMBER : 146-17-8 BEILSTEIN REFERENCE NO. : 0068086 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C17-H21-N4-O9-P MOLECULAR WEIGHT : 456.39 WISWESSER LINE NOTATION : T C666 BM DVMVM INTT&J I1YQYQYQ1OPQQO L1 M1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 365 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 20 ug/plate REFERENCE : ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 45,327,1981

合成路线

83-88-5 ~% 146-17-8

文献：Helvetica Chimica Acta, , vol. 35, p. 451,455

116081-53-9 ~% 146-17-8

文献：Chemische Berichte, , vol. 69, p. 1543,1546

4846-23-5 83-88-5 ~% 146-17-8

文献：Chemical and Pharmaceutical Bulletin, , vol. 7, p. 465,467

986-54-9 ~% 146-17-8

文献：Bulletin of the Korean Chemical Society, , vol. 34, # 1 p. 31 - 32

1498-51-7 83-88-5 ~% 146-17-8

文献：Proceedings of the Japan Academy, , vol. 29, p. 260

677-24-7 83-88-5 ~% 146-17-8

文献：Proceedings of the Japan Academy, , vol. 29, p. 260

7732-18-5 146-14-5 ~% 1088-56-8 61-19-8 详细

文献：Yakugaku Zasshi, , vol. 75, p. 799 Chem.Abstr., , p. 16341 Med. J. Osaka Univ. Chem.Abstr., , vol. 10, p. 513,516 Med. J. Osaka Univ. Chem.Abstr., , p. 13832

7647-01-0 146-14-5 ~% 1088-56-8 61-19-8 详细

文献：Yakugaku Zasshi, , vol. 75, p. 799 Chem.Abstr., , p. 16341 Biochemische Zeitschrift, , vol. 298, p. 150,156

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