5689-59-8

• 常用中文名：1-氯乙酰氨基金刚烷
• 常用英文名：N-(1-adamantyl)-2-chloroacetamide
• CAS号：5689-59-8
• 分子式：C₁₂H₁₈ClNO
• 分子量：227.73000
• 发布时间：2018-03-31 08:00:00
• 更新时间：2024-01-02 17:33:32

名称

• 中文名: 1-氯乙酰氨基金刚烷
• 英文名: N-(1-adamantyl)-2-chloroacetamide
• 中文别名: N-氯乙酰基-1-氨基金刚烷; N-1-金刚烷-2-氯乙酰胺

物化性质

• 密度: 1.2g/cm3
• 沸点: 385.3ºC at 760mmHg
• 熔点: 120-121ºC
• 分子式: C₁₂H₁₈ClNO
• 分子量: 227.73000
• 闪点: 186.8ºC
• 精确质量: 227.10800
• PSA: 29.10000
• LogP: 2.70110
• 折射率: 1.547

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AB4309000 CHEMICAL NAME : Acetamide, N-(1-adamantyl)-2-chloro- CAS REGISTRY NUMBER : 5689-59-8 LAST UPDATED : 199712 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C12-H18-Cl-N-O MOLECULAR WEIGHT : 227.76 WISWESSER LINE NOTATION : L66 B6/B-H/DI A B- C 1B ITJ BMV1G HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 760 mg/kg TOXIC EFFECTS : Behavioral - rigidity (including catalepsy) Behavioral - antipsychotic REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 14,185,1980

安全

• 危害码 (欧洲): Xi
• 海关编码: 2924299090

合成路线

768-95-6 ~% 5689-59-8

文献：Journal of Organic Chemistry USSR (English Translation), , vol. 18, p. 867 - 871 Zhurnal Organicheskoi Khimii, , vol. 18, # 5 p. 1001 - 1005

768-94-5 79-04-9 ~92% 5689-59-8

文献：Giordanetto, Fabrizio; Knerr, Laurent; Selmi, Nidhal; Llins, Antonio; Lindqvist, Anders; Wang, Qing-Dong; Sthlberg, Pernilla; Thorstensson, Fredrik; Ullah, Victoria; Nilsson, Kristina; O'Mahony, Gavin; Hoegberg, Got; Lindhardt, Emma; Strand, Annika; Duker, Goeran Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5557 - 5561

768-95-6 107-14-2 ~98% 5689-59-8

文献：HEXAL AG Patent: WO2007/96124 A1, 2007 ; Location in patent: Page/Page column 14 ;

593-71-5 4411-25-0 ~95% 5689-59-8

文献：Pace, Vittorio; Castoldi, Laura; Holzer, Wolfgang Chemical Communications, 2013 , vol. 49, # 75 p. 8383 - 8385

665-66-7 79-04-9 ~96% 5689-59-8

文献：Onajole, Oluseye K.; Govender, Patrick; Helden, Paul D. van; Kruger, Hendrik G.; Maguire, Glenn E.M.; Wiid, Ian; Govender, Thavendran European Journal of Medicinal Chemistry, 2010 , vol. 45, # 5 p. 2075 - 2079

768-95-6 79-07-2 ~79% 5689-59-8

文献：Shokova; Musulu, Tasula; Luzikov; Kovalev Russian Journal of Organic Chemistry, 1999 , vol. 35, # 6 p. 844 - 856

上下游产品

上游产品  8
768-94-5 79-04-9 768-95-6 107-14-2
593-71-5 4411-25-0 665-66-7 79-07-2
下游产品  3
37818-93-2 768-94-5 53783-83-8

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%