49669-14-9

• 常用中文名：2-溴-6-(2-甲基-1,3-二氧戊烷-2-基)吡啶
• 常用英文名：2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine
• CAS号：49669-14-9
• 分子式：C₉H₁₀BrNO₂
• 分子量：244.085
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 吡啶衍生物
• 发布时间：2018-12-10 18:13:17
• 更新时间：2024-01-07 18:50:37

名称

• 中文名: 2-溴-6-(2-甲基-1,3-二氧戊烷-2-基)吡啶
• 英文名: 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine
• 中文别名: 2-溴-6-(2-甲基-1,3-二氧杂烷)吡啶; 2-溴-6-乙酰基吡啶乙二醇保护; 2-溴-6-(2-甲基-1,3-二氧戊环-2-基)吡啶; 2-溴-6-(2-甲基-1,3-二氧戊环-2-基)吡啶
• 英文别名: 2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine; RW1992; Pyridine, 2-bromo-6-(2-methyl-1,3-dioxolan-2-yl)-

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 322.7±42.0 °C at 760 mmHg
• 熔点: 44-46℃
• 分子式: C₉H₁₀BrNO₂
• 分子量: 244.085
• 闪点: 148.9±27.9 °C
• 精确质量: 242.989487
• PSA: 31.35000
• LogP: 1.48
• 外观性状: 固体;White to Light yellow powder to crystal
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.550
• 储存条件: 2~8℃

MSDS

2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine SAFETY DATA SHEET Section1. IDENTIFICATION Product name:2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine 5.3 Section2. HAZARDS IDENTIFICATION GHS classification PHYSICAL HAZARDSNot classified Not classified HEALTH HAZARDS ENVIRONMENTAL HAZARDSNot classified GHS label elements, including precautionary statements Pictograms or hazard symbolsNone No signal word Signal word Hazard statementsNone None Precautionary statements: Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substance/mixture:Substance Components:2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine Percent:>98.0%(GC) CAS Number:49669-14-9 Chemical Formula:C9H10BrNO2 Section4. FIRST AID MEASURES Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical advice/attention if you feel unwell. Skin contact:Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. If skin irritation or rash occurs: Get medical advice/attention. Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. Ingestion:Get medical advice/attention if you feel unwell. Rinse mouth. A rescuer should wear personal protective equipment, such as rubber gloves and air- Protection of first-aiders: tight goggles. Section5. FIRE-FIGHTING MEASURES Suitable extinguishingDry chemical, foam, water spray, carbon dioxide. media: Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to from the chemical:generate poisonous fume. Section5. FIRE-FIGHTING MEASURES Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so. Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment. equipment for firefighters: Section6. ACCIDENTAL RELEASE MEASURES Use personal protective equipment. Keep people away from and upwind of spill/leak. Personal precautions, protective equipment and Entry to non-involved personnel should be controlled around the leakage area by emergency procedures: roping off, etc. Environmental precautions: Prevent product from entering drains. Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it. containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with up: appropriate laws and regulations. Section7. HANDLING AND STORAGE Precautions for safe handling Handling is performed in a well ventilated place. Wear suitable protective equipment. Technical measures: Prevent dispersion of dust. Wash hands and face thoroughly after handling. Use a local exhaust if dust or aerosol will be generated. Advice on safe handling: Avoid contact with skin, eyes and clothing. Conditions for safe storage, including any incompatibilities Storage conditions:Keep container tightly closed. Store in a cool and dark place. Store away from incompatible materials such as oxidizing agents. Packaging material:Comply with laws. Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION Install a closed system or local exhaust as possible so that workers should not be Engineering controls: exposed directly. Also install safety shower and eye bath. Personal protective equipment Respiratory protection: Dust respirator. Follow local and national regulations. Hand protection:Protective gloves. Eye protection:Safety glasses. A face-shield, if the situation requires. Skin and body protection: Protective clothing. Protective boots, if the situation requires. Section9. PHYSICAL AND CHEMICAL PROPERTIES Physical state (20°C):Solid Form:Crystal- Powder Colour:Very pale yellow - Pale yellow Odour:No data available pH: No data available Melting point/freezing point:45°C No data available Boiling point/range: Flash point:No data available Flammability or explosive limits: No data available Lower: Upper:No data available No data available Relative density: Solubility(ies): No data available [Water] [Other solvents]No data available Section10. STABILITY AND REACTIVITY Chemical stability:Stable under proper conditions. Possibility of hazardous No special reactivity has been reported. reactions: Incompatible materials: Oxidizing agents Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen bromide products: Section11. TOXICOLOGICAL INFORMATION No data available Acute Toxicity: Skin corrosion/irritation: No data available No data available Serious eye damage/irritation: Germ cell mutagenicity: No data available Carcinogenicity: IARC =No data available NTP =No data available No data available Reproductive toxicity: Section12. ECOLOGICAL INFORMATION Ecotoxicity: No data available Fish: Crustacea:No data available Algae:No data available Persistence / degradability: No data available BioaccumulativeNo data available potential(BCF): Mobility in soil Log Pow:No data available No data available Soil adsorption (Koc): Henry's LawNo data available constant(PaM3/mol): Section13. DISPOSAL CONSIDERATIONS Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section14. TRANSPORT INFORMATION Hazards Class:Does not correspond to the classification standard of the United Nations Not listed UN-No: Section15. REGULATORY INFORMATION Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002 and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were prescribed. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi
• 海关编码: 2932999099

合成路线

49669-13-8 107-21-1 ~87% 49669-14-9

文献：Ronson, Tanya K.; Adams, Harry; Harding, Lindsay P.; Pope, Simon J. A.; Sykes, Daniel; Faulkner, Stephen; Ward, Michael D. Dalton Transactions, 2007 , # 10 p. 1006 - 1022

626-05-1 ~% 49669-14-9

文献：Poellnitz, Alpar; Skupienski, Radek; Stoeckli-Evans, Helen; Crochet, Aurelien; Silvestru, Anca; Fromm, Katharina M.; Mamula, Olimpia Synlett, 2013 , vol. 24, # 19 art. no. ST-2013-B0678-L, p. 2555 - 2558

上下游产品

上游产品  3
49669-13-8 107-21-1 626-05-1
下游产品  4
190125-80-5 20857-21-0 122637-39-2 122637-38-1

海关

海关编码	2932999099
中文概述	2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%