217195-91-0

• 常用中文名：2-羟基-2-(三氟甲基)-4-甲基-4-戊酸乙酯
• 常用英文名：ethyl 2-hydroxy-2-(trifluoromethyl)-4-methylpent-4-enoate 97
• CAS号：217195-91-0
• 分子式：C₉H₁₃F₃O₃
• 分子量：226.193
• 发布时间：2019-01-02 00:11:39
• 更新时间：2024-01-21 21:30:41

名称

• 中文名: 2-羟基-2-(三氟甲基)-4-甲基-4-戊酸乙酯
• 英文名: ethyl 2-hydroxy-2-(trifluoromethyl)-4-methylpent-4-enoate 97
• 中文别名: 2-羟基-2-(三氟甲基)-4-甲基-4-戊烯酸乙酯
• 英文别名: Ethyl 2-hydroxy-4-methyl-2-(trifluoromethyl)pent-4-enoate; 4-Pentenoic acid, 2-hydroxy-4-methyl-2-(trifluoromethyl)-, ethyl ester; 2-hydroxy-4-methyl-2-trifluoromethylpent-4-enoic acid ethyl ester; Ethyl 2-hydroxy-4-methyl-2-(trifluoromethyl)-4-pentenoate

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 243.1±35.0 °C at 760 mmHg
• 分子式: C₉H₁₃F₃O₃
• 分子量: 226.193
• 闪点: 100.8±25.9 °C
• 精确质量: 226.081680
• PSA: 46.53000
• LogP: 3.32
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.411

安全

• 海关编码: 2918199090

合成路线

1458-98-6 13081-18-0 ~73% 217195-91-0

文献：Intendis GmbH Patent: EP1982976 A1, 2008 ; Location in patent: Page/Page column 8 ;

13081-18-0 21969-32-4 ~60% 217195-91-0

文献：BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. Patent: WO2005/30213 A1, 2005 ; Location in patent: Page/Page column 195-196 ; WO 2005/030213 A1

3017-69-4 13081-18-0 ~53% 217195-91-0

文献：BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. Patent: WO2003/82787 A1, 2003 ; Location in patent: Page/Page column 106 ; WO 03/082787 A1

13081-18-0 ~% 217195-91-0

文献：WO2007/122165 A1, ; Page/Page column 59-61 ;

13081-18-0 115-11-7 ~% 217195-91-0

文献：EP2098501 A1, ; Page/Page column 18-19; 29-30 ;

115-11-7 ~88% 217195-91-0

文献：SCHERING AKTIENGESELLSCHAFT Patent: WO2006/50998 A1, 2006 ; Location in patent: Page/Page column 34-35 ;

7439-96-5 3017-69-4 84638-12-0 ~50% 217195-91-0

文献：Boehringer Ingelheim Pharmaceuticals, Inc. Patent: US2004/10148 A1, 2004 ; US 20040010148 A1

13081-18-0 5674-01-1 ~61% 217195-91-0

文献：Riether, Doris; Harcken, Christian; Razavi, Hossein; Kuzmich, Daniel; Gilmore, Thomas; Bentzien, Joerg; Pack, Edward J.; Souza, Donald; Nelson, Richard M.; Kukulka, Alison; Fadra, Tazmeen N.; Zuvela-Jelaska, Ljiljana; Pelletier, Josephine; Dinallo, Roger; Panzenbeck, Mark; Torcellini, Carol; Nabozny, Gerald H.; Thomson, David S. Journal of Medicinal Chemistry, 2010 , vol. 53, # 18 p. 6681 - 6698

上下游产品

上游产品  8
1458-98-6 13081-18-0 21969-32-4 3017-69-4
115-11-7 7439-96-5 84638-12-0 5674-01-1
下游产品  1
609806-82-8

海关

海关编码	2918199090
中文概述	HS: 2918199090. 其他含醇基但不含其他含氧基羧酸（包括其酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%