33224-23-6

• 常用中文名：4-甲氧基-3-硝基苯甲腈
• 常用英文名：4-METHOXY-3-NITROBENZONITRILE
• CAS号：33224-23-6
• 分子式：C₈H₆N₂O₃
• 分子量：178.14500
• 发布时间：2018-03-02 08:00:00
• 更新时间：2024-01-14 14:27:22

名称

• 中文名: 4-甲氧基-3-硝基苯甲腈
• 英文名: 4-methoxy-3-nitrobenzonitrile
• 英文别名: 3-Nitro-anissaeure-nitril; 2-Nitro-4-cyanoanisol; 4-methoxy-3-nitrobenzenecarbonitrile; 4-Methoxy-3-nitro-benzonitril; 3-Nitro-4-methoxy-benzoesaeure-nitril; 5-Cyano-2-methoxynitrobenzene; 3-Nitro-4-methoxybenzonitrile; 4-methoxy-3-nitro-benzonitrile

物化性质

• 密度: 1.32g/cm3
• 沸点: 330.2ºC at 760mmHg
• 熔点: 148-150ºC
• 分子式: C₈H₆N₂O₃
• 分子量: 178.14500
• 闪点: 153.5ºC
• 精确质量: 178.03800
• PSA: 78.84000
• LogP: 1.99828
• 折射率: 1.563
• 储存条件: 室温

MSDS

Name: 4-Methoxy-3-nitrobenzonitrile 97% Material Safety Data Sheet Synonym: CAS: 33224-23-6 Section 1 - Chemical Product MSDS Name:4-Methoxy-3-nitrobenzonitrile 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 33224-23-6 4-Methoxy-3-nitrobenzonitrile unlisted Hazard Symbols: XN Risk Phrases: 20/21/22 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Harmful if inhaled. Causes respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 33224-23-6: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 148 - 150 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C8H6N2O3 Molecular Weight: 178 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Acids, bases, oxidizing agents, reducing agents. Hazardous Decomposition Products: Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 33224-23-6 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-Methoxy-3-nitrobenzonitrile - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: NITRILES, SOLID, TOXIC, N.O.S.* Hazard Class: 6.1 UN Number: 3276 Packing Group: III IMO Shipping Name: NITRILES, TOXIC, N.O.S. Hazard Class: 6.1 UN Number: 3276 Packing Group: III RID/ADR Shipping Name: NITRILES, TOXIC, N.O.S. Hazard Class: 6.1 UN Number: 3276 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 33224-23-6: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 33224-23-6 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 33224-23-6 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xn:Harmful;
• 风险声明 (欧洲): 20/21/22-36/37/38
• 安全声明 (欧洲): 26-36/37/39
• 危险品运输编码: UN 3276
• 海关编码: 2926909090

合成路线

874-90-8 ~97% 33224-23-6

文献：Aridoss, Gopalakrishnan; Laali, Kenneth K. Journal of Organic Chemistry, 2011 , vol. 76, # 19 p. 8088 - 8094

3272-08-0 74-88-4 ~74% 33224-23-6

文献：Bakunov, Stanislav A.; Bakunova, Svetlana M.; Wenzler, Tanja; Ghebru, Maedot; Werbovetz, Karl A.; Brun, Reto; Tidwell, Richard R. Journal of Medicinal Chemistry, 2010 , vol. 53, # 1 p. 254 - 272

3272-08-0 77-78-1 ~99% 33224-23-6

文献：RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a.; RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY Patent: EP1222183 B1, 2003 ;

186581-53-3 3272-08-0 ~% 33224-23-6

文献：Magnetic Resonance in Chemistry, , vol. 30, # 6 p. 497 - 499

3424-93-9 ~% 33224-23-6

文献：Chemische Berichte, , vol. 2, p. 666

939-80-0 124-41-4 ~% 33224-23-6

文献：Recueil des Travaux Chimiques des Pays-Bas, , vol. 66, p. 369 Chem.Abstr., , vol. 42, p. 148

89642-49-9 124-41-4 ~% 33224-23-6

文献：Recueil des Travaux Chimiques des Pays-Bas, , vol. 41, p. 106,107

上下游产品

上游产品  9
874-90-8 3272-08-0 74-88-4 77-78-1
186581-53-3 3424-93-9 939-80-0 124-41-4
89642-49-9
下游产品  4
19018-96-3 60979-25-1 10397-58-7 124839-61-8

海关

海关编码	2926909090
中文概述	2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%