78327-30-7

• 常用中文名：{(1AS,8S,8aR,8bS)-8a-methoxy-5-methyl-4,7-dioxo-6-[(tetrahydrofuran-2-ylmethyl)amino]-1,1a,2,4,7,8,8a,8b-octahydroazireno[2,3:3,4]pyrrolo[1,2-a]indol-8-yl}methyl carbamate
• 常用英文名：{(1AS,8S,8aR,8bS)-8a-methoxy-5-methyl-4,7-dioxo-6-[(tetrahydrofuran-2-ylmethyl)amino]-1,1a,2,4,7,8,8a,8b-octahydroazireno[2,3:3,4]pyrrolo[1,2-a]indol-8-yl}methyl carbamate
• CAS号：78327-30-7
• 分子式：C₂₀H₂₆N₄O₆
• 分子量：418.444
• 发布时间：2016-12-07 12:10:03
• 更新时间：2024-02-15 01:57:15

名称

• 英文名: ((1AS,8S,8aR,8bS)-8a-methoxy-5-methyl-4,7-dioxo-6-((tetrahydrofuran-2-ylmethyl)amino)-1,1a,2,4,7,8,8a,8b-octahydroazireno(2',3':3,4)pyrrolo(1,2-a)indol-8-yl)methyl carbamate
• 英文别名: Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-6-[[(tetrahydro-2-furanyl)methyl]amino]-, (1aS,8S,8aR,8bS)-; {(1aS,8S,8aR,8bS)-8a-Methoxy-5-methyl-4,7-dioxo-6-[(tetrahydro-2-furanylmethyl)amino]-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl}methyl carbamate; {(1AS,8S,8aR,8bS)-8a-methoxy-5-methyl-4,7-dioxo-6-[(tetrahydrofuran-2-ylmethyl)amino]-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl}methyl carbamate; ((1AS,8S,8aR,8bS)-8a-methoxy-5-methyl-4,7-dioxo-6-((tetrahydrofuran-2-ylmethyl)amino)-1,1a,2,4,7,8,8a,8b-octahydroazireno(2',3':3,4)pyrrolo(1,2-a)indol-8-yl)methyl carbamate

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 656.1±55.0 °C at 760 mmHg
• 分子式: C₂₀H₂₆N₄O₆
• 分子量: 418.444
• 闪点: 350.6±31.5 °C
• 精确质量: 418.185242
• PSA: 142.13000
• LogP: 1.04
• 蒸汽压: 0.0±2.0 mmHg at 25°C
• 折射率: 1.644

合成路线

4795-29-3 4055-39-4 ~44% 78327-30-7

文献：Iyengar, Bhashyam S.; Lin, Horng-Jau; Cheng, Leung; Remers, William A.; Bradner, William T. Journal of Medicinal Chemistry, 1981 , vol. 24, # 8 p. 975 - 981

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