CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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QL0840000
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CHEMICAL NAME :
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Naphtho(2,1-b)furan, 7-methoxy-2-nitro-
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CAS REGISTRY NUMBER :
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75965-74-1
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LAST UPDATED :
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199612
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DATA ITEMS CITED :
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19
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MOLECULAR FORMULA :
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C13-H9-N-O4
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MOLECULAR WEIGHT :
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243.23
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WISWESSER LINE NOTATION :
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T B566 EOJ DNW KO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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210 mg/kg/91W-C
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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24 mg/kg/36W-I
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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11967 ug/kg
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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20 mg/kg/10W-I
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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360 mg/kg/12W-I
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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10 mg/kg/5W-I
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
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TYPE OF TEST :
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Sperm Morphology
MUTATION DATA
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TYPE OF TEST :
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Mutation test systems - not otherwise specified
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TEST SYSTEM :
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Bird - chicken Embryo
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DOSE/DURATION :
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1 mg/L
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REFERENCE :
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AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 23,328,1983
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