127626-37-3

• 常用中文名：多尼培南中间体
• 常用英文名：(2S,TRANS)-4-NITROBENZYL 2-(HYDROXYMETHYL)-4-((METHYLSULFONYL)OXY)PYRROLIDINE-1-CARBOXYLATE
• CAS号：127626-37-3
• 分子式：C₁₄H₁₈N₂O₈S
• 分子量：374.366
• 发布时间：2018-04-10 08:00:00
• 更新时间：2024-01-05 20:03:22

名称

• 中文名: 多尼培南中间体
• 英文名: (4-nitrophenyl)methyl (2S,4R)-2-(hydroxymethyl)-4-methylsulfonyloxypyrrolidine-1-carboxylate
• 中文别名: (2S,4R)-2-羟甲基-4-甲磺酰氧基-1-吡咯烷羧酸 (4-硝基苯基)甲基酯
• 英文别名: 1-Pyrrolidinecarboxylic acid, 2-(hydroxymethyl)-4-[(methylsulfonyl)oxy]-, (4-nitrophenyl)methyl ester, (2S,4R)-; (2S,4R)-1-p-nitrobenzyloxycarbonyl-4-methanesulfonyloxypyrrolidine-2-methanol; (2S,4R)-2-hydroxymethyl-4-methanesulfonyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine; 4-Nitrobenzyl (2S,4R)-2-(hydroxymethyl)-4-[(methylsulfonyl)oxy]-1-pyrrolidinecarboxylate; (2S,trans)-4-Nitrobenzyl 2-(hydroxymethyl)-4-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate; (2S,4R)-2-hydroxymethyl-4-methylsulfonyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine; (2S,4R)-2-(Hydroxymethyl)-4-[(methylsulfonyl)oxy]-1-pyrrolidinecarboxylic acid (4-nitrophenyl)methyl ester

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 619.8±55.0 °C at 760 mmHg
• 熔点: 113-116ºC
• 分子式: C₁₄H₁₈N₂O₈S
• 分子量: 374.366
• 闪点: 328.6±31.5 °C
• 精确质量: 374.078400
• PSA: 147.34000
• LogP: -0.45
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.607

合成路线

138324-82-0 ~80% 127626-37-3

文献：Lee; Lim; Kang; Yoo; Kim; Shin European Journal of Medicinal Chemistry, 2006 , vol. 41, # 11 p. 1347 - 1351

51-35-4 ~% 127626-37-3

文献：European Journal of Medicinal Chemistry, , vol. 41, # 11 p. 1347 - 1351

4457-32-3 ~% 127626-37-3

文献：European Journal of Medicinal Chemistry, , vol. 41, # 11 p. 1347 - 1351

40216-83-9 ~% 127626-37-3

文献：European Journal of Medicinal Chemistry, , vol. 41, # 11 p. 1347 - 1351

101803-29-6 ~% 127626-37-3

文献：European Journal of Medicinal Chemistry, , vol. 41, # 11 p. 1347 - 1351

96034-57-0 ~% 127626-37-3

文献：Organic Process Research and Development, , vol. 7, # 5 p. 649 - 654

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