96034-57-0

• 常用中文名：反式-4-羟基-1-(4-硝基苄氧基羰基)-L-脯氨酸
• 常用英文名：trans-4-hydroxy-1-(4-nitrobenzyloxycarbonyl)-l-proline
• CAS号：96034-57-0
• 分子式：C₁₃H₁₄N₂O₇
• 分子量：310.259
• 相关类别： 原料药 抗生素类药物 β-内酰胺酶抑制剂
• 发布时间：2018-06-01 08:00:00
• 更新时间：2026-07-24 19:04:33

名称

• 中文名: 1,2-二羧基吡咯烷酸,4-羟基-1-[(4-硝基苯基)甲基]酯
• 英文名: (2S,4R)-4-hydroxy-1-[(4-nitrophenyl)methoxycarbonyl]pyrrolidine-2-carboxylic acid
• 中文别名: 美罗培南杂质TN-1; 反-4-羟基-1-(4-硝基苄氧羰基)-L-脯氨酸; 美罗培南杂质12; (2S,4R)-1-(4-硝基苄氧羰基)-4-羟基脯氨酸; 美罗培南杂质18; O粉; 多瑞培南杂质1; 多尼培南中间体3; (2S,4R)-4-羟基-1-(((4-硝基苄基)氧基)羰基)吡咯烷-2-羧酸多尼培南中间体3
• 英文别名: P-NITRO BENZYL 2(S) CBOXY TRANS 4(R) HYDROXY L P; TRANS-4-HYDROXY-1-(4-NITROBENZYLOXYCBONYL)-L-PROLINE; (2S,4R)-1-((4-NITROBENZYLOXY)carbonyl)-4-HYDROXYPYRROLIDINE-2-CBOXYLIC ACID; 1,2-Pyrrolidinedicboxylicacid, 4-hydroxy-, 1-[(4-nitrophenyl)methyl] ester, (2S,4R); (2S,4R)-4-hydroxy-1-p-nitrobenzyloxycbonyl-2-pyrrolidinecboxylic acid; Donipenem intermediate 3; (2S,4S)-4-nitrobenzyl 4-mercapto-2-(methylcbamoyl)pyrrolidine-1-cboxylate; 1,2-Pyrrolidinedicboxylic acid, 4-hydroxy-, 1-[(4-nitrophenyl)methyl] ester, (2S,4R); 1,2-Pyrrolidinedicboxylic acid, 4-hydroxy-, 1-[(4-nitrophenyl)Methyl] ester; (2S,4R)-4-Hydroxy-1-(4-nitrobenzyloxycbonyl)pyrrolidine-2-cboxylic acid; TRANS-4-HYDROXY-1-(4-NITROBENZYLOXYCBONYL)-L-PROLINE //BP; (2S,4R)-4-Hydroxy-1,2-pyrrolidinedicboxylic Acid 1-(4-Nitrobenzyl) Ester; Meropenem Impurity 18; (4R)-4-Hydroxy-1-{[(4-nitrobenzyl)oxy]carbonyl}-L-proline; (2S,4R)-1-(4-Nitrobenzyloxycbonyl)-4-hydroxyproline; (2S,4R)-4-hydroxy-1-[(4-nitrophenyl)methoxycbonyl]pyrrolidine-2-cboxylic acid; (2S,4R)-4-hydroxy-1-[(4-nitrophenyl)methoxycbonyl]pyrrolidine-2-cboxylicaci

物化性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 578.3±50.0 °C at 760 mmHg
• 熔点: 182-183℃
• 分子式: C₁₃H₁₄N₂O₇
• 分子量: 310.259
• 闪点: 303.5±30.1 °C
• 精确质量: 310.080109
• PSA: 132.89000
• LogP: -0.37
• 外观性状: Solid
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.639
• 储存条件: 室温

安全

• 海关编码: 2933990090

合成路线

51-35-4 4457-32-3 ~95% 96034-57-0

文献：Kang, Yong Koo; Shin, Kye Jung; Yoo, Kyung Ho; Seo, Kyung Jae; Hong, Chang Yong; Lee, Chang-Seok; Park, Seung Yong; Kim, Dong Jin; Park, Sang Woo Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 2 p. 95 - 99

619-73-8 ~% 96034-57-0

文献：Journal of the American Chemical Society, , vol. 74, p. 3818,3819

上下游产品

上游产品  3
51-35-4 4457-32-3 619-73-8
下游产品  5
96036-03-2 96036-02-1 96034-64-9 127626-37-3
138324-82-0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%