59653-66-6

• 常用中文名：(S)-(-)-2-(α-(异丙基甲酰胺)-1H-苯并咪唑
• 常用英文名：1H-Benzimidazole-2-methanamine,alpha-(1-methylethyl)-,(S)-(9CI)
• CAS号：59653-66-6
• 分子式：C₁₁H₁₅N₃
• 分子量：189.25700
• 发布时间：2018-12-16 16:40:52
• 更新时间：2024-04-03 07:25:08

名称

• 中文名: (s)-(9ci)-alpha-(1-甲基乙基)-1H-苯并咪唑-2-甲胺
• 英文名: 1-(1H-benzimidazol-2-yl)-2-methylpropan-1-amine
• 英文别名: ZLB0034; 1-benzimidazol-2-yl-2-methylpropylamine

物化性质

• 分子式: C₁₁H₁₅N₃
• 分子量: 189.25700
• 精确质量: 189.12700
• PSA: 54.70000
• LogP: 2.91900

MSDS

Section 1: Product Identification Chemical Name:(S)-(-)-2-(alpha-(i-propyl)methanamine)-1H-benzimidazole, min. 98% (S)-i-Pr-BIMAH CAS Registry Number:59653-66-6 Formula:C11H15N3 EINECS Number:none Chemical Family:organic amine Synonym:(S)-i-Pr-BIMAH; (S)-(-)-1-(1H-benzo[d]imidazol-2-yl)-2-methylpropan-1-amine Section 2: Composition and Information on Ingredients IngredientCAS NumberPercentACGIH (TWA)OSHA (PEL) Title compound59653-66-6100%no datano data Section 3: Hazards Identification Emergency Overview:Irritating to skin, eyes and respiratory tract. Primary Routes of Exposure:Ingestion, inhalation, eyes Eye Contact:Dust causes moderate irritation of the eyes. Skin Contact:Causes slight to mild irritation of the skin. Inhalation:Irritating to the nose, mucous membranes and respiratory tract. Ingestion:No information available on the physiological effects of ingestion. May be harmful if swallowed. Acute Health Affects:Irritating to skin, eyes and respiratory tract. Chronic Health Affects:No information on long-term chronic effects. NTP:No IARC:No OSHA:No SECTION 4: First Aid Measures Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need Eye Exposure: assistance in keeping their eye lids open. Get immediate medical attention. Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if Skin Exposure: irritation persists. Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty Inhalation: in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance. Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce Ingestion: vomiting only if directed by medical personnel. SECTION 5: Fire Fighting Measures Flash Point:none Autoignition Temperature:none Explosion Limits:none Extinguishing Medium:carbon dioxide, dry powder or foam If this product is involved in a fire, fire fighters should be equipped with a NIOSH approved positive pressure Special Fire Fighting Procedures: self-contained breathing apparatus and full protective clothing. Hazardous Combustion andIf involved in a fire this material may emit irritating fumes. Decomposion Products: Unusual Fire or Explosion Hazards: No unusual fire or explosion hazards. SECTION 6: Accidental Release Measures Spill and Leak Procedures:Small spills can be mixed with vermiculite or sodium carbonate and swept up. SECTION 7: Handling and Storage Store in a tightly sealed container under an inert atmosphere of nitrogen or argon. Keep in a cool, dry, Handling and Storage: well-ventilated place. SECTION 8: Exposure Controls and Personal Protection Eye Protection:Always wear approved safety glasses when handling a chemical substance in the laboratory. Skin Protection:Wear protective clothing and gloves. Ventilation:Handle the material in an efficient fume hood. If ventilation is not available a respirator should be worn. The use of respirators requires a Respirator Respirator: Protection Program to be in compliance with 29 CFR 1910.134. Ventilation:Handle the material in an efficient fume hood. Additional Protection:No additional protection required. SECTION 9: Physical and Chemical Properties Color and Form:white to off-white solid Molecular Weight:189.26 Melting Point:166-168 ° Boiling Point:no data Vapor Pressure:no data Specific Gravity:no data Odor:none Solubility in Water:insoluble SECTION 10: Stability and Reactivity Stability:air sensitive Hazardous Polymerization:no hazardous polymerization Conditions to Avoid:prolonged exposure to air Incompatibility:strong oxidizing agents Decomposition Products:carbon monoxide, carbon dioxide, nitrogen oxides, and organic fumes SECTION 11: Toxicological Information RTECS Data:No information available in the RTECS files. Carcinogenic Effects:no data Mutagenic Effects:no data Tetratogenic Effects:no data SECTION 12: Ecological Information Ecological Information:No information available SECTION 13: Disposal Considerations Disposal:Dispose of according to local, state and federal regulations. SECTION 14: Transportation Shipping Name (CFR):Non-hazardous Hazard Class (CFR):NA Additional Hazard Class (CFR):NA Packaging Group (CFR):NA UN ID Number (CFR):NA Shipping Name (IATA):Non-hazardous Hazard Class (IATA):NA Additional Hazard Class (IATA):NA Packaging Group (IATA):NA UN ID Number (IATA):NA SECTION 15: Regulatory Information TSCA:Not listed in the TSCA inventory SARA (Title 313):Not regulated under SARA 313 Second Ingredient:none SECTION 16 - ADDITIONAL INFORMATION N/A

合成路线

1419561-77-5 ~% 59653-66-6

文献：Ghosh, Kumaresh; Sarkar, Tanmay Supramolecular Chemistry, 2012 , vol. 24, # 10 p. 748 - 754,7

72-18-4 95-54-5 ~43% 59653-66-6

文献：Li, Yuehui; Ding, Kuiling; Sandoval, Christian A. Organic Letters, 2009 , vol. 11, # 4 p. 907 - 910

13734-41-3 ~% 59653-66-6

文献：Ghosh, Kumaresh; Sarkar, Tanmay Supramolecular Chemistry, 2012 , vol. 24, # 10 p. 748 - 754,7

133703-84-1 ~% 59653-66-6

文献：Ghosh, Kumaresh; Sarkar, Tanmay Supramolecular Chemistry, 2012 , vol. 24, # 10 p. 748 - 754,7

95-54-5 ~% 59653-66-6

文献：Ghosh, Kumaresh; Sarkar, Tanmay Supramolecular Chemistry, 2012 , vol. 24, # 10 p. 748 - 754,7

59592-11-9 ~% 59653-66-6

文献：Zhang, Datong; Wang, Zongheng; Xu, Weiren; Sun, Fanggang; Tang, Lida; Wang, Jianwu European Journal of Medicinal Chemistry, 2009 , vol. 44, # 5 p. 2202 - 2210

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