652990-07-3

• 常用中文名：Milveterol
• 常用英文名：Milveterol
• CAS号：652990-07-3
• 分子式：C₂₅H₂₉N₃O₄
• 分子量：435.51500
• 发布时间：2016-12-17 19:43:13
• 更新时间：2024-01-09 23:48:26
• Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold).

名称

• 英文名: N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[2-[4-[[(2R)-2-hydroxy-2-phenylethyl]amino]phenyl]ethylamino]ethyl]phenyl]formamide
• 英文别名: Milveterol; UNII-LGY1VQ9622

物化性质

• 分子式: C₂₅H₂₉N₃O₄
• 分子量: 435.51500
• 精确质量: 435.21600
• PSA: 117.34000
• LogP: 4.08510

合成路线

652990-10-8 ~89% 652990-07-3

文献：GLAXO GROUP LIMITED Patent: WO2005/95328 A1, 2005 ; Location in patent: Page/Page column 25-26 ;

13472-00-9 ~% 652990-07-3

文献：Jacobsen, John R.; Choi, Seok Ki; Combs, Jesse; Fournier, Eric J.L.; Klein, Uwe; Pfeiffer, Juergen W.; Thomas, G. Roger; Yu, Cecile; Moran, Edmund J. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 1213 - 1218

344466-46-2 ~% 652990-07-3

文献：Jacobsen, John R.; Choi, Seok Ki; Combs, Jesse; Fournier, Eric J.L.; Klein, Uwe; Pfeiffer, Juergen W.; Thomas, G. Roger; Yu, Cecile; Moran, Edmund J. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 1213 - 1218

344466-47-3 ~% 652990-07-3

文献：Jacobsen, John R.; Choi, Seok Ki; Combs, Jesse; Fournier, Eric J.L.; Klein, Uwe; Pfeiffer, Juergen W.; Thomas, G. Roger; Yu, Cecile; Moran, Edmund J. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 1213 - 1218

1355183-83-3 ~% 652990-07-3

文献：Jacobsen, John R.; Choi, Seok Ki; Combs, Jesse; Fournier, Eric J.L.; Klein, Uwe; Pfeiffer, Juergen W.; Thomas, G. Roger; Yu, Cecile; Moran, Edmund J. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 1213 - 1218

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