70458-93-4

• 常用中文名：7-氯-6-氟-4-4羟基-3-喹啉甲酸乙酯
• 常用英文名：ethyl 7-chloro-6-fluoro-4-hydroxyquinoline-3-carboxylate
• CAS号：70458-93-4
• 分子式：C₁₂H₉ClFNO₃
• 分子量：269.65600
• 发布时间：2018-12-27 21:45:59
• 更新时间：2024-01-02 09:32:43

名称

• 中文名: 7-氯-6-氟-4-4羟基-3-喹啉甲酸乙酯
• 英文名: ethyl 7-chloro-6-fluoro-4-oxo-1H-quinoline-3-carboxylate
• 英文别名: 7-chloro-3-ethoxycarbonyl-6-fluoro-4-hydroxyquinoline; 7-chloro-6-fluoro-4-hydroxyquinoline-3-carboxylic acid; 7-chloro-6-fluoro-4-hydroxyquinoline-3-carboxylic acid ethyl ester; Ethyl 7-chloro-6-fluoro-4-hydroxyquinoline-3-carboxylate; 7-Chloro-6-fluoro-4-hydroxy-3-quinolinecarboxylic acid ethyl ester

物化性质

• 密度: 1.416g/cm3
• 沸点: 384.5ºC at 760 mmHg
• 分子式: C₁₂H₉ClFNO₃
• 分子量: 269.65600
• 闪点: 186.4ºC
• 精确质量: 269.02500
• PSA: 59.16000
• LogP: 2.49730
• 折射率: 1.564

合成路线

70032-30-3 ~89% 70458-93-4

文献：CENTRO MARGA PARA LA INVESTIGACION S.A. Patent: EP376870 A1, 1990 ;

367-21-5 87-13-8 ~% 70458-93-4

文献：Saxena, Anil K.; Roy, Kuldeep K.; Singh, Supriya; Vishnoi; Kumar, Anil; Kashyap, Vivek Kr.; Kremer, Laurent; Srivastava, Ranjana; Srivastava, Brahm S. International Journal of Antimicrobial Agents, 2013 , vol. 42, # 1 p. 27 - 35

367-21-5 70032-30-3 87-13-8 ~% 70458-93-4

文献：Laboratorie Roger Bellon; Dainippon Pharmaceutical Patent: US4292317 A1, 1981 ; US 4292317 A

367-21-5 ~% 70458-93-4

文献：Koga, Hiroshi; Itoh, Akira; Murayama, Satoshi; Suzue, Seigo; Irikura, Tsutomu Journal of Medicinal Chemistry, 1980 , vol. 23, # 12 p. 1358 - 1363

87-13-8 ~% 70458-93-4

文献：Koga, Hiroshi; Itoh, Akira; Murayama, Satoshi; Suzue, Seigo; Irikura, Tsutomu Journal of Medicinal Chemistry, 1980 , vol. 23, # 12 p. 1358 - 1363