194594-24-6

• 常用中文名：5-甲氧基吡咯烷-1,2-二羧酸-(2S)-1-叔丁基-2-乙酯
• 常用英文名：(2S)-1-TERT-BUTYL 2-ETHYL 5-METHOXYPYRROLIDINE-1,2-DICARBOXYLATE
• CAS号：194594-24-6
• 分子式：C₁₃H₂₃NO₅
• 分子量：273.325
• 发布时间：2018-12-25 15:14:44
• 更新时间：2024-01-16 18:20:49

名称

• 中文名: 5-甲氧基吡咯烷-1,2-二羧酸-(2S)-1-叔丁基-2-乙酯
• 英文名: 1-O-tert-butyl 2-O-ethyl (2S)-5-methoxypyrrolidine-1,2-dicarboxylate
• 英文别名: ethyl (2S,5R/S)-1-(tert-butoxycarbonyl)-5-methoxypyrrolidine-2-carboxylate; (2S)-1-tert-Butyl 2-ethyl 5-methoxypyrrolidine-1,2-dicarboxylate; 1,2-Pyrrolidinedicarboxylic acid, 5-methoxy-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S)-; 2-Ethyl 1-(2-methyl-2-propanyl) (2S)-5-methoxy-1,2-pyrrolidinedicarboxylate; 1-tert-Butyl 2-ethyl (2S)-5-methoxypyrrolidine-1,2-dicarboxylate; Boc-5-metoxy-L-proline ethyl ester; (2S,5R/S)-1-(tert-butoxycarbonyl)-5-methoxypyrrolidine-2-carboxylic acid ethyl ester

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 333.1±42.0 °C at 760 mmHg
• 分子式: C₁₃H₂₃NO₅
• 分子量: 273.325
• 闪点: 155.3±27.9 °C
• 精确质量: 273.157623
• PSA: 65.07000
• LogP: 1.12
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.478

安全

• 海关编码: 2933990090

合成路线

67-56-1 194594-23-5 ~93% 194594-24-6

文献：FORSCHUNGSVERBUND BERLIN E.V. Patent: US2011/34438 A1, 2011 ; Location in patent: Page/Page column 26 ;

144978-35-8 ~% 194594-24-6

文献：Pichon, Marianne; Figadere, Bruno; Cave, Andre Tetrahedron Letters, 1996 , vol. 37, # 44 p. 7963 - 7966

7149-65-7 ~% 194594-24-6

文献：FORSCHUNGSVERBUND BERLIN E.V. Patent: US2011/34438 A1, 2011 ;

67-56-1 144978-35-8 ~% 194594-24-6

文献：Zhang, Xiaojun; Schmitt, Aaron C.; Jiang, Wen; Wasserman, Zelda; Decicco, Carl P. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 6 p. 1157 - 1160

98-79-3 ~% 194594-24-6

文献：FORSCHUNGSVERBUND BERLIN E.V. Patent: US2011/34438 A1, 2011 ;

24424-99-5 ~% 194594-24-6

文献：St-Denis, Yves; Augelli-Szafran, Corinne E.; Bachand, Benoit; Berryman, Kent A.; DiMaio, John; Doherty, Annette M.; Edmunds, Jeremy J.; Leblond, Lorraine; Levesque, Sophie; Narasimhan, Lakshmi S.; Penvose-Yi, Jan R.; Rubin, J. Ronald; Tarazi, Micheline; Winocour, Peter D.; Siddiqui, M. Arshad Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 22 p. 3193 - 3198

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%