81078-84-4

• 常用中文名：4-哌嗪-1-基-呋喃并吡啶
• 常用英文名：4-(Piperazin-1-yl)furo[3,2-c]pyridine
• CAS号：81078-84-4
• 分子式：C₁₁H₁₃N₃O
• 分子量：203.240
• 发布时间：2018-03-17 08:00:00
• 更新时间：2024-01-09 06:37:22

名称

• 中文名: 4-哌嗪-1-基-呋喃并吡啶
• 英文名: 4-(Piperazin-1-yl)furo[3,2-c]pyridine
• 英文别名: 4-Piperazin-1-yl-furo[3,2-c]pyridine; Furo[3,2-c]pyridine, 4-(1-piperazinyl)-; 4-(1-Piperazinyl)furo[3,2-c]pyridine; 4-piperazin-1-ylfuro[3,2-c]pyridine

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 378.8±32.0 °C at 760 mmHg
• 熔点: 58ºC
• 分子式: C₁₁H₁₃N₃O
• 分子量: 203.240
• 闪点: 182.9±25.1 °C
• 精确质量: 203.105865
• PSA: 41.30000
• LogP: 0.64
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.608
• 储存条件: 2-8°C

MSDS

Name: 4-Piperazin-1-yl-furo[3 2-c]pyridine Material Safety Data Sheet Synonym: None Known CAS: 81078-84-4 Section 1 - Chemical Product MSDS Name:4-Piperazin-1-yl-furo[3 2-c]pyridine Material Safety Data Sheet Synonym:None Known Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 81078-84-4 4-Piperazin-1-yl-furo[3,2-c]pyridine 95+% unlisted Hazard Symbols: C Risk Phrases: 22 34 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful if swallowed. Causes burns. Potential Health Effects Eye: Causes eye burns. Skin: Causes skin burns. Ingestion: Harmful if swallowed. Causes gastrointestinal tract burns. Inhalation: Causes chemical burns to the respiratory tract. Chronic: Chronic exposure may cause effects similar to those of acute exposure. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid immediately. Wash clothing before reuse. Ingestion: If swallowed, do NOT induce vomiting. Get medical aid immediately. If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use foam, dry chemical, or carbon dioxide. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use only in a chemical fume hood. Discard contaminated shoes. Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 81078-84-4: Personal Protective Equipment Eyes: Wear chemical splash goggles and face shield. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Oil Color: Pale yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C11H13N3O Molecular Weight: 203.25 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 81078-84-4 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-Piperazin-1-yl-furo[3,2-c]pyridine - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Ecotoxicity: Fish: Pseudomonas putida: Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: CORROSIVE LIQUID, TOXIC, N.O.S. Hazard Class: 8 (6.1) UN Number: 2922 Packing Group: II IMO Shipping Name: CORROSIVE LIQUID, TOXIC, N.O.S. Hazard Class: 8 (6.1) UN Number: 2922 Packing Group: II RID/ADR Shipping Name: CORROSIVE LIQUID, TOXIC, N.O.S. Hazard Class: 8 (6.1) UN Number: 2922 Packing group: II Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 22 Harmful if swallowed. R 34 Causes burns. Safety Phrases: S 23 Do not inhale gas/fumes/vapour/spray. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 81078-84-4: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 81078-84-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 81078-84-4 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi
• 海关编码: 2934999090

合成路线

110-85-0 31270-80-1 ~82% 81078-84-4

文献：New, James S.; Christopher, William L.; Yevich, Joseph P.; Butler, Rhett; Schlemmer, R. Francis; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 6 p. 1147 - 1156

20689-54-7 ~% 81078-84-4

文献：Journal of Medicinal Chemistry, , vol. 32, # 6 p. 1147 - 1156

59898-36-1 ~% 81078-84-4

文献：Journal of Medicinal Chemistry, , vol. 32, # 6 p. 1147 - 1156

26956-43-4 ~% 81078-84-4

文献：Journal of Medicinal Chemistry, , vol. 32, # 6 p. 1147 - 1156

539-47-9 ~% 81078-84-4

文献：Journal of Medicinal Chemistry, , vol. 32, # 6 p. 1147 - 1156

上下游产品

上游产品  6
110-85-0 31270-80-1 20689-54-7 59898-36-1
26956-43-4 539-47-9
下游产品  0

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%