131287-39-3

• 常用中文名：Fmoc-L-Asn(GlcNAc(Ac)3-β)-OH
• 常用英文名：fmoc-asn(ac3acnh-beta-glc)-oh
• CAS号：131287-39-3
• 分子式：C₃₃H₃₇N₃O₁₃
• 分子量：683.65900
• 相关类别： 生物化工 氨基酸及其衍生物 天冬酰胺类衍生物
• 发布时间：2018-12-26 17:22:50
• 更新时间：2026-07-07 19:49:22
• Fmoc-L-Asn(β-D-GlcNAc(Ac)3)-OH(Fmoc-Asn(Ac3AcNH-β-Glc)-OH)可用于合成氟化硅受体(SiFA)衍生的奥曲酸衍生物。SiFA奥曲酸类似物作为肿瘤显像剂,是正电子发射断层扫描(PET)研究的有用工具[1]。

名称

• 中文名: N-(9-芴甲氧羰基)-N’-(2-乙酰氨基-2-脱氧-3,4,6-三-O-乙酰基-beta-D-吡喃葡萄糖基)-L-天冬酰胺
• 英文名: (2S)-4-[[(2R,3R,4R,5S,6R)-3-acetamido-4,5-diacetyloxy-6-(acetyloxymethyl)oxan-2-yl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxobutanoic acid
• 中文别名: 四乙酰氨基葡萄糖L-N-FMOC-天冬酰胺; (S)-2-((((9H-芴-9-基)甲氧基)羰基)氨基)-4-(((2R,3R,4R,5S,6R)-3-乙酰氨基-4,5-二乙酰氧基-6-(乙酰氧基甲基)四氢-2H-吡喃-2-基)氨基)-4-氧代丁酸; N-(9-芴甲氧羰基)-N'-(2-乙酰氨基-2-脱氧-3,4,6-三-O-乙酰基-BETA-D-吡喃葡萄糖基)-L-天冬酰胺; FMOC-谷氨酰胺(BETA-D-N-乙酰胺-O-三乙酰葡萄糖); N-(9-芴甲氧羰基)-N`-(2-乙酰氨基-2-脱氧-3,4,6-三-O-乙酰基-beta-D-吡喃葡萄糖基)-L-天冬酰胺; N-(9-芴甲氧羰基)-N'-(2-乙酰氨基-2-脱氧-3,4,6-三-O-乙酰基-D-吡喃葡萄糖基)-L-天冬酰胺
• 英文别名: Fmoc-Asn(GlcNAc(Ac)-β-D)-OH; 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucopyranosyl-Fmoc-aspagine; FMoc-Asn(GlcNAc(Ac)3-b-D)-OH; Fmoc-Asn(β-D-GlcNAc(Ac)3-OH; Fmoc-L-Asn(GlcNAc(Ac)3-beta)-OH; Na-Fmoc-Ng-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-b-glucopyranosyl)-L-aspagine (HPLC); FMoc-Asn(β-D-GlcNAc(Ac)3)-OH; MFCD00237079; Fmoc-L-Asn(2-D-GlcNAc(Ac)3-OH; N-(9-Fluorenylmethoxycbonyl)-N'-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-BETA-D-glucopyranosyl)-L-aspagine; FMOC-ASN(AC3ACNH-BETA-GLC)-OH //BP; L-Aspagine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]; N-ALPHA-(9-FLUORENYLMETHYLOXYCBONYL)-N-BETA-(2-ACETAMIDO-2-DEOXY-3,4,6-TRI-O-ACETYL-BETA-D-GLUCOPYRANOSYL)-L-ASPAGINE; Fmoc-Asn(GlcNAc(Ac)-β-D)-OH; N-ALPHA-FMOC-N-BETA-(3,4,6-TRI-O-ACETYL-2-(ACETYLAMINO)-DEOXY-2-BETA-GLUCOPYRANOSYL)-L-ASPAGINE; Fmoc-ASN(Ac3AcNH-β-GLC)-OH; N-(9-Fluorenylmethyloxycbonyl)-N'-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-beta-D-glucopyranosyl)-L-aspagine; FMOC-ASN(GLCNAC(AC)3-B)-OH; (2S)-4-[[(2R,3R,4R,5S,6R)-3-acetamido-4,5-diacetyloxy-6-(acetyloxymethyl)oxan-2-yl]amino]-2-(9H-fluoren-9-ylmethoxycbonylamino)-4-oxobutanoicaci; FMOC-ASPAGINE(GLCNAC(AC)3-BETA-D)-OH; N-ALPHA-(9-FLUORENYLMETHYLOXYCBONYL)-N-GAMMA-(2-ACETAMIDO-2DEOXY-3,4,6-TRI-O-ACETYL-BETA-D-GALACTOPYRANOSYL)-L-ASPAGIN; Fmoc-Asn(GlcNAc(Ac)3-β-D)-OH; fmoc-asn(a; Fmoc-L-Asn(GlcNAc4)-OH; (2S)-4-[[(2R,3R,4R,5S,6R)-3-acetamido-4,5-diacetyloxy-6-(acetyloxymethyl)oxan-2-yl]amino]-2-(9H-fluoren-9-ylmethoxycbonylamino)-4-oxobutanoic acid; Fmoc-Asn(b-D-GlcNAc(Ac)3)-OH; FMOC-ASN(GLCNAC(AC)3-BETA-D)-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(((2R,3R,4R,5S,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)amino)-4-oxobutanoic acid; N-ALPHA-FMOC-N-GAMMA-(2-ACETAMIDO-2-DEOXY-3,4,6-TRI-O-ACETYL-BETA-D-GLUCOPYRANOSYL)-L-ASPAGINE; Fmoc-Asn(Ac3GlcNAcβ)-OH; Fmoc-Asn(β-D- GlcNHAc(Ac)3)-OH; Fmoc-L-Asn(GlcNAc(Ac)3-b)-OH; (S)-2-(((9H-fluoren-9-yl)methyl9H-fluoren-9-yl)methoxy)cbonylamino)-4-((2R,3R,4R,5S,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-ylamino)-4-oxobutanoic acid; N-FMOC-N-ALPHA-(2-ACETAMIDO-3,4,6-TRI-O-ACETYL-2-DEOXY-BETA-D-GLUCOPYRANOSYL)-L-ASPAGINE; 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-Fmoc-aspagine; N-a-FMoc-N-g-(2-acetaMido-2-deoxy-3,4,6-tri-O-acetyl-b-D-glucopyranosyl)-L-aspagine; (N-ALPHA-FMOC-N-GAMMA-(2-ACETAMIDO-2-DEOXY-3,4,6-TRI-O-ACETYL-BETA-GLUCOPYRANOSYL)-L-ASPAGINE); Fmoc-L-Asn(β-D-GlcNAc(Ac)3)-OH; FMOC-L-ASN(GLCNAC)-OH; 2N-Fmoc-92-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl)-L-aspagine; 3-{[4,5-BIS(ACETYLOXY)-6-[(ACETYLOXY)METHYL]-3-ACETAMIDOOXAN-2-YL]CBAMOYL}-2-{[(9H-FLUOREN-9-YLMET; Fmoc-L-Asn((Ac)3-beta-D-GlcNAc)-OH >= (HPLC); Fmoc-Asn(AcAcNH--Glc)-OH; Fmoc-L-Asn(β-D-GlcNAc(Ac)3-OH; N-ALPHA-(9-FLUORENYLMETHOXYCBONYL)-N-GAMMA-(2-ACETAMIDE-2-DEOXY-3,4,6-TRI-O-ACETYL-BETA-D-GLUCOPYRANOSYL)-L-ASPAGINE; GLCNAC L-ASPAGINE; FMOC-ASN(AC3ACNH-BETA-GLC)-OH; 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl-Fmoc-aspagine; N-alpha-Fmoc-N-gamma-(2-acetamido-2-deoxy-3,4,6-tr; Fmoc-L-Asn((Ac)3-β-D-GlcNAc)-OH; Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH; N-alpha-(9-Fluorenylmethyloxycbonyl)-N-gamma-(2-acetamido-2deoxy-3,4,6-tri-O-acetyl-beta-D-glucopyranosyl)-L-aspagin

物化性质

• 分子式: C₃₃H₃₇N₃O₁₃
• 分子量: 683.65900
• 精确质量: 683.23300
• PSA: 221.96000
• LogP: 2.31340
• 储存条件: -15°C

生物活性

• 描述: Fmoc-L-Asn(β-D-GlcNAc(Ac)3)-OH(Fmoc-Asn(Ac3AcNH-β-Glc)-OH)可用于合成氟化硅受体(SiFA)衍生的奥曲酸衍生物。SiFA奥曲酸类似物作为肿瘤显像剂,是正电子发射断层扫描(PET)研究的有用工具[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Wängler C, et al. One-step ^¹⁸F-labeling of carbohydrate-conjugated octreotate-derivatives containing a silicon-fluoride-acceptor (SiFA): in vitro and in vivo evaluation as tumor imaging agents for positron emission tomography (PET). Bioconjug Chem. 2010;21(12):2289-2296.

安全

• 危险品运输编码: NONH for all modes of transport

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