1257-78-9

• 常用中文名：丙氯拉嗪乙二磺酸盐
• 常用英文名：prochlorperazine edisylate
• CAS号：1257-78-9
• 分子式：C₂₂H₃₀ClN₃O₆S₃
• 分子量：564.13800
• 发布时间：2016-10-02 18:39:29
• 更新时间：2024-01-31 14:34:22

名称

• 中文名: 丙氯拉嗪乙二磺酸盐
• 英文名: prochlorperazine edisylate
• 英文别名: 2-CHLORO-10-[3-(4-METHYL-1-PIPERAZINYL)PROPYL]PHENOTHIAZINE 1,2-ETHANEDISULFONATE (1:1); 2-chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazineedisylate; 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine1,2-ethanedisulfo; PROCHLORPERAZINE ETHANE DISULFONATE; ethane-1,2-disulphonic acid,compound with 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine (1:1); prochlorperazine edisylate usp; 2-chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazinethanedisulfona

物化性质

• 沸点: 524.8ºC at 760 mmHg
• 分子式: C₂₂H₃₀ClN₃O₆S₃
• 分子量: 564.13800
• 闪点: 271.2ºC
• 精确质量: 563.09900
• PSA: 160.52000
• LogP: 5.44460
• 蒸汽压: 4.15E-11mmHg at 25°C
• 储存条件: 2-8℃

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SO2975000 CHEMICAL NAME : Phenothiazine, 2-chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-, ethanedisulfonate CAS REGISTRY NUMBER : 1257-78-9 LAST UPDATED : 199504 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C20-H24-Cl-N3-S.C2-H6-O6-S2 MOLECULAR WEIGHT : 564.18 WISWESSER LINE NOTATION : T C666 BN ISJ EG B3- AT6N DNTJ D1 &WSQ2SWQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,40,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 177 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 12,142,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 320 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,40,1972 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 350 mg/kg SEX/DURATION : female 7-20 day(s) after conception TOXIC EFFECTS : Reproductive - Maternal Effects - parturition Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) Reproductive - Effects on Newborn - behavioral REFERENCE : SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 205,1220,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3225 No. of Facilities: 70 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 4939 (estimated) No. of Female Employees: 4444 (estimated)

安全

• 危害码 (欧洲): Xn
• 风险声明 (欧洲): 22
• RTECS号: SO2975000